CD74 [clathrin-coated endocytic vesicle membrane]

Stable Identifier
R-HSA-2130522
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
clathrin-coated endocytic vesicle membrane
Synonyms
Invariant chain (Ii), HLA class II histocompatibility antigen gamma chain, HG2A_HUMAN
Locations in the PathwayBrowser
Expand all
External Reference Information
External Reference
UniProt:P04233 CD74
Gene Names
CD74, DHLAG
Chain
chain:1-296, peptide:97-120
Reference Genes
BioGPS Gene:972 CD74
COSMIC (genes):CD74 CD74
CTD Gene:972 CD74
dbSNP Gene:972 CD74
ENSEMBL:ENSG00000019582 CD74
HGNC:1697 CD74
KEGG Gene (Homo sapiens):972 CD74
Monarch:972 CD74
NCBI Gene:972 CD74
OMIM:142790 CD74
UCSC:P04233 CD74
Reference Transcript
Other Identifiers
0006510088
11726254_s_at
11726255_x_at
11738435_x_at
11739401_a_at
11756766_x_at
1567628_at
17001654
209619_at
2881371
2881372
2881373
2881374
2881375
2881376
2881377
2881378
2881379
2881380
2881381
2881384
2881386
2881387
2881391
2881393
2881396
2881398
2881400
2881401
2881407
2881408
2881409
2881410
35016_at
40595_at
8115147
972
A_23_P70095
GE79594
GO:0000139
GO:0000187
GO:0001516
GO:0001540
GO:0001934
GO:0001961
GO:0002250
GO:0002286
GO:0002376
GO:0002606
GO:0002792
GO:0002830
GO:0002906
GO:0003674
GO:0004896
GO:0005515
GO:0005575
GO:0005576
GO:0005615
GO:0005622
GO:0005634
GO:0005737
GO:0005764
GO:0005765
GO:0005768
GO:0005770
GO:0005771
GO:0005773
GO:0005783
GO:0005789
GO:0005794
GO:0005886
GO:0006457
GO:0006464
GO:0006629
GO:0006810
GO:0006886
GO:0006950
GO:0006952
GO:0006955
GO:0007155
GO:0007165
GO:0008150
GO:0008219
GO:0008283
GO:0009058
GO:0009897
GO:0009986
GO:0010628
GO:0012507
GO:0015031
GO:0016020
GO:0016021
GO:0016064
GO:0019882
GO:0019883
GO:0019886
GO:0019899
GO:0019955
GO:0022607
GO:0023026
GO:0030154
GO:0030336
GO:0030658
GO:0030666
GO:0030669
GO:0030890
GO:0031394
GO:0031410
GO:0032588
GO:0032755
GO:0032757
GO:0032991
GO:0033674
GO:0034641
GO:0035691
GO:0035692
GO:0035693
GO:0035718
GO:0040011
GO:0042289
GO:0042592
GO:0042609
GO:0042613
GO:0042658
GO:0042802
GO:0043030
GO:0043066
GO:0043123
GO:0043202
GO:0043226
GO:0043410
GO:0043518
GO:0044183
GO:0044281
GO:0044403
GO:0045058
GO:0045059
GO:0045060
GO:0045080
GO:0045581
GO:0045582
GO:0045657
GO:0045893
GO:0046598
GO:0048146
GO:0048856
GO:0048870
GO:0050731
GO:0050900
GO:0050998
GO:0051085
GO:0060907
GO:0065003
GO:0070062
GO:0070206
GO:0070374
GO:0071556
GO:0090023
GO:1902166
GO:2000343
GO:2000448
Hs2.438626.1.S1_3p_at
ILMN_1736567
ILMN_1761464
ILMN_2379644
M13560_s_at
PH_hs_0027479
TC05001936.hg
TC05003305.hg
g188469_3p_at
g188469_3p_x_at
Participant Of
hasComponent
Other forms of this molecule
CD74(81-104) [lysosomal lumen]
CD74(81-104) [lysosomal membrane]
CD74(1-117) [lysosomal membrane]
CD74 [ER to Golgi transport vesicle membrane]
CD74 [integral component of lumenal side of endoplasmic reticulum membrane]
CD74 [Golgi membrane]
CD74 [trans-Golgi network membrane]
CD74 [transport vesicle membrane]
CD74 [endocytic vesicle membrane]
CD74(1-176) [lysosomal membrane]
CD74 [lysosomal membrane]
CD74 [plasma membrane]
Inferred To
Cd74 [clathrin-coated endocytic vesicle membrane] (Mus musculus)
Cd74 [clathrin-coated endocytic vesicle membrane] (Rattus norvegicus)
Ii [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
cd74 [clathrin-coated endocytic vesicle membrane] (Xenopus tropicalis)
CD74 [clathrin-coated endocytic vesicle membrane] (Canis familiaris)
CD74 [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
cd74a [clathrin-coated endocytic vesicle membrane] (Danio rerio)
Cross References
RefSeq
OpenTargets
HPA
GeneCards
ZINC - Substances
Ensembl
ZINC target
PRO
ZINC - Predictions - Purchasable
PDB
Interactors (8)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:P01909 HLA-DQA1  9 0.589 2
 UniProt:P61073 CXCR4  1 0.556 4
 UniProt:P40939 HADHA  1 0.547 2
 UniProt:P0A6Y8 DNAK      0.544 8
 UniProt:P08107 HSP71      0.544 3
 UniProt:P60228 EIF3E  1 0.499 2
 UniProt:Q14974 KPNB1  5 0.499 2
 UniProt:P16070 CD44  2 0.463 9
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