CD74 [clathrin-coated endocytic vesicle membrane]

Stable Identifier
R-HSA-2130522
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
clathrin-coated endocytic vesicle membrane
Synonyms
Invariant chain (Ii), HLA class II histocompatibility antigen gamma chain, HG2A_HUMAN
Locations in the PathwayBrowser
Expand all
External Reference Information
External Reference
UniProt:P04233 CD74
Gene Names
CD74, DHLAG
Chain
chain:1-296
Reference Genes
BioGPS Gene:972 CD74
COSMIC (genes):CD74 CD74
CTD Gene:972 CD74
dbSNP Gene:972 CD74
ENSEMBL:ENSG00000019582 CD74
HGNC:1697 CD74
KEGG Gene (Homo sapiens):972 CD74
Monarch:972 CD74
NCBI Gene:972 CD74
OMIM:142790 CD74
UCSC:P04233 CD74
Reference Transcript
Other Identifiers
0006510088
10592
11726254_s_at
11726255_x_at
11738435_x_at
11739401_a_at
11756766_x_at
1567628_at
17001654
1A6A
1ICF
1IIE
1L3H
1MUJ
209619_at
2506
2881371
2881372
2881373
2881374
2881375
2881376
2881377
2881378
2881379
2881380
2881381
2881384
2881386
2881387
2881391
2881393
2881396
2881398
2881400
2881401
2881407
2881408
2881409
2881410
35016_at
3PDO
3PGC
3PGD
3QXA
3QXD
40595_at
4AEN
4AH2
4X5W
5KSU
5KSV
8115147
972
A_23_P70095
AAA36033
AAA36304
AAH18726
AAH24272
AAV38312
AC011372
AC011388
AK292076
AK297889
BAF84765
BAG60210
BC018726
BC024272
BT019505
CAA25192
CAA25193
CAA27046
CAA27047
CAB002506
CCDS34276
CCDS47308
CCDS47309
CD74
CD74-201
CD74-202
CD74-203
CH471062
E7EQJ3
E7ER71
E7ESL3
EAW61727
EAW61728
EAW61729
EAW61730
EAW61731
ENSG00000019582
ENSP00000009530
ENSP00000230685
ENSP00000367026
ENST00000009530
ENST00000009530.11
ENST00000353334
ENST00000353334.10
ENST00000377795
ENST00000377795.7
EntrezGene:972
EntrezGene:CD74
g188469_3p_at
g188469_3p_x_at
GE79594
GO:0000139
GO:0000187
GO:0001516
GO:0001540
GO:0001934
GO:0001961
GO:0002250
GO:0002376
GO:0002606
GO:0002792
GO:0002830
GO:0002906
GO:0003674
GO:0004896
GO:0005515
GO:0005575
GO:0005576
GO:0005615
GO:0005622
GO:0005623
GO:0005634
GO:0005737
GO:0005764
GO:0005765
GO:0005768
GO:0005770
GO:0005771
GO:0005773
GO:0005783
GO:0005789
GO:0005794
GO:0005886
GO:0006457
GO:0006464
GO:0006629
GO:0006810
GO:0006886
GO:0006950
GO:0006952
GO:0006955
GO:0007155
GO:0007165
GO:0008150
GO:0008219
GO:0008283
GO:0009058
GO:0009897
GO:0009986
GO:0010628
GO:0012507
GO:0016020
GO:0016021
GO:0016064
GO:0019882
GO:0019883
GO:0019886
GO:0019899
GO:0019955
GO:0022607
GO:0023026
GO:0030154
GO:0030336
GO:0030658
GO:0030666
GO:0030669
GO:0030890
GO:0031394
GO:0031410
GO:0032588
GO:0032991
GO:0033674
GO:0034641
GO:0035691
GO:0035692
GO:0035693
GO:0035718
GO:0040011
GO:0042289
GO:0042592
GO:0042609
GO:0042613
GO:0042658
GO:0042802
GO:0043030
GO:0043066
GO:0043123
GO:0043202
GO:0043226
GO:0043410
GO:0043518
GO:0044183
GO:0044281
GO:0044403
GO:0045058
GO:0045059
GO:0045060
GO:0045080
GO:0045410
GO:0045416
GO:0045581
GO:0045582
GO:0045657
GO:0045893
GO:0046598
GO:0048146
GO:0048856
GO:0048870
GO:0050731
GO:0050900
GO:0050998
GO:0051085
GO:0051290
GO:0060907
GO:0065003
GO:0070062
GO:0070206
GO:0070374
GO:0071556
GO:0090023
GO:1902166
GO:2000343
GO:2000448
HGNC:1697
HPA010592
Hs2.438626.1.S1_3p_at
ILMN_1736567
ILMN_1761464
ILMN_2379644
IPR000716
IPR011988
IPR015386
IPR022339
IPR036613
IPR036857
K01144
M13555
M13556
M13558
M13559
M13560
M13560_s_at
MIM:142790
NM_001025158
NM_001025159
NM_001364083
NM_001364084
NM_004355
NP_001020329
NP_001020330
NP_001351012
NP_001351013
NP_004346
PF00086
PF08831
PF09307
PH_hs_0027479
PR01990
SM00211
TC05001936.hg
TC05003305.hg
UPI000002AB09
UPI000008AF52
UPI000012C6BB
X00497
X03339
X03340
Participant Of
hasComponent
Other forms of this molecule
CD74(81-104) [lysosomal lumen]
CD74(81-104) [lysosomal membrane]
CD74(1-117) [lysosomal membrane]
CD74 [transport vesicle membrane]
CD74 [plasma membrane]
CD74 [lysosomal membrane]
CD74(1-176) [lysosomal membrane]
CD74 [trans-Golgi network membrane]
CD74 [Golgi membrane]
CD74 [integral component of lumenal side of endoplasmic reticulum membrane]
CD74 [ER to Golgi transport vesicle membrane]
CD74 [endocytic vesicle membrane]
Inferred To
CD74 [clathrin-coated endocytic vesicle membrane] (Bos taurus)
CD74 [clathrin-coated endocytic vesicle membrane] (Canis familiaris)
CD74 [clathrin-coated endocytic vesicle membrane] (Danio rerio)
CD74 [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
CD74 [clathrin-coated endocytic vesicle membrane] (Mus musculus)
CD74 [clathrin-coated endocytic vesicle membrane] (Rattus norvegicus)
CD74 [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
CD74 [clathrin-coated endocytic vesicle membrane] (Xenopus tropicalis)
Cross References
RefSeq
OpenTargets
GeneCards
ZINC - Substances
ZINC target
PRO
ZINC - Predictions - Purchasable
PDB
Interactors (8)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:P01909 HLA-DQA1  9 0.589 2
 UniProt:P61073 CXCR4  1 0.556 4
 UniProt:P40939 HADHA  1 0.547 2
 UniProt:P0A6Y8 DNAK      0.544 8
 UniProt:P0DMV8 HSPA1A  4 0.544 3
 UniProt:P60228 EIF3E  1 0.499 2
 UniProt:Q14974 KPNB1  5 0.499 2
 UniProt:P16070 CD44  2 0.463 9