Synthesis of 5-eicosatetraenoic acids

Stable Identifier
R-HSA-2142688
Type
Pathway
Species
Homo sapiens
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Synthesis of 5-eicosatetraenoic acids
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5-hydroperoxy-eicosatetraenoic acid (5-HpETE), 5-hydroxyeicosatetraenoic acid (5S-HETE) and 5-oxo-eicosatetraenoic acid (5-oxoETE) are formed after the initial step of arachidonic acid oxidation by arachidonate 5-lipoxygenase (ALOX5) (Buczynski et al. 2009, Vance & Vance 2008).

Literature References
PubMed ID Title Journal Year
19244215 Thematic Review Series: Proteomics. An integrated omics analysis of eicosanoid biology

Buczynski, MW, Dumlao, DS, Dennis, EA

J Lipid Res 2009
  Biochemistry of Lipids, Lipoproteins and Membranes, 5th Edition

Vance, DE, Vance, JE

  2008
Participants
Events
Participant Of
hasEvent
Event Information
Go Biological Process
lipoxygenase pathway (0019372)
Orthologous Events
Synthesis of 5-eicosatetraenoic acids (Bos taurus)
Synthesis of 5-eicosatetraenoic acids (Caenorhabditis elegans)
Synthesis of 5-eicosatetraenoic acids (Canis familiaris)
Synthesis of 5-eicosatetraenoic acids (Danio rerio)
Synthesis of 5-eicosatetraenoic acids (Dictyostelium discoideum)
Synthesis of 5-eicosatetraenoic acids (Gallus gallus)
Synthesis of 5-eicosatetraenoic acids (Mus musculus)
Synthesis of 5-eicosatetraenoic acids (Rattus norvegicus)
Synthesis of 5-eicosatetraenoic acids (Sus scrofa)
Synthesis of 5-eicosatetraenoic acids (Xenopus tropicalis)
Cross References
BioModels Database
Authored
Williams, MG  (2012-02-24)
Reviewed
Rush, MG  (2012-11-10)
Created
Williams, MG  (2012-02-24)