Synthesis of 15-eicosatetraenoic acid derivatives

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R-HSA-2142770
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Homo sapiens
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The 15-eicosatetraenoic acids: 15-hydroperoxy-eicosatetraenoic acid (15-HpETE), 15-hydroxyeicosatetraenoic acid (15-HETE) and 15-oxo-eicosatetraenoic acid (15-oxoETE) are formed after the initial step of arachidonic acid oxidation by the arachidonate 15-lipoxygenases (ALOX15 and ALOX15B) (Buczynski et al. 2009, Vance & Vance 2008).

Literature References
PubMed ID Title Journal Year
19244215 Thematic Review Series: Proteomics. An integrated omics analysis of eicosanoid biology

Buczynski, MW, Dumlao, DS, Dennis, EA

J Lipid Res 2009
  Biochemistry of Lipids, Lipoproteins and Membranes, 5th Edition

Vance, DE, Vance, JE

  2008
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