Reactome | TNC [extracellular region]

TNC [extracellular region]

Stable Identifier

R-HSA-215968

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

extracellular region

Synonyms

Tenascin, TN-C

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:P24821 TNC

Gene Names

TNC, HXB

Chain

signal peptide:1-22, chain:23-2201

Reference Genes

BioGPS Gene:3371 TNC

COSMIC (genes):TNC TNC

CTD Gene:3371 TNC

dbSNP Gene:3371 TNC

ENSEMBL:ENSG00000041982 TNC

HGNC:5318 TNC

KEGG Gene (Homo sapiens):3371 TNC

Monarch:3371 TNC

NCBI Gene:3371 TNC

OMIM:187380 TNC

UCSC:P24821 TNC

Reference Transcript

Other Identifiers

0003520390

11716062_a_at

11716063_at

11747935_a_at

11752009_a_at

17097661

201645_at

237169_at

3222171

3222172

3222173

3222174

3222175

3222176

3222177

3222181

3222183

3222184

3222186

3222187

3222188

3222190

3222192

3222193

3222194

3222195

3222198

3222205

3222210

3222212

3222214

3222215

3222216

3222219

3222220

3222221

3222222

3222225

3222226

3222227

3222228

3222229

3222230

3222231

3222234

3222235

3222253

3222254

3222255

32818_at

3371

75075_at

8163637

GE62327

GO:0000003

GO:0001649

GO:0003674

GO:0005198

GO:0005201

GO:0005515

GO:0005575

GO:0005576

GO:0005604

GO:0005614

GO:0005615

GO:0005622

GO:0005737

GO:0005783

GO:0005788

GO:0005925

GO:0006464

GO:0006950

GO:0007155

GO:0007162

GO:0007267

GO:0007528

GO:0008150

GO:0008283

GO:0008284

GO:0009611

GO:0009612

GO:0010628

GO:0014012

GO:0016020

GO:0030154

GO:0030198

GO:0031012

GO:0031175

GO:0034330

GO:0040007

GO:0042060

GO:0042127

GO:0042475

GO:0043226

GO:0043687

GO:0044267

GO:0045471

GO:0045545

GO:0048856

GO:0060447

GO:0060739

GO:0060740

GO:0062023

GO:0071300

GO:0071305

GO:0071774

GO:0071799

GO:0098966

Hs.135261.0.A1_3p_at

ILMN_1719759

ILMN_2145670

PH_hs_0035499

TC09001517.hg

X78565_at

g4504548_3p_at

Participant Of

hasComponent

input

Other forms of this molecule

p-TNC [endoplasmic reticulum lumen]

TNC [endoplasmic reticulum lumen]

Inferred To

sadA [extracellular region] (Dictyostelium discoideum)

tnc [extracellular region] (Danio rerio)

rpl5 [extracellular region] (Xenopus tropicalis)

TNC [extracellular region] (Caenorhabditis elegans)

TNC [extracellular region] (Canis familiaris)

Tnc [extracellular region] (Mus musculus)

Tnc [extracellular region] (Rattus norvegicus)

Cross References

RefSeq

XP_005252031.1, XP_011516931.1, XP_005252032.1, NP_002151.2, XP_005252029.1

Target Pathogen

5b354852be737e166372e766

OpenTargets

ENSG00000041982

GeneCards

P24821

HPA

ENSG00000041982-TNC

Ensembl

ENSP00000265131, ENST00000537320, ENSP00000443478, ENSG00000041982, ENST00000350763

PRO

P24821

Orphanet

22607

PDB

6BRB, 6QNV, 2RBL, 1TEN, 2RB8

Interactors (1)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P20908 COL5A1	72	3x4Hyp-GlcGalHyl-COL5A1(38-1838) [endoplasmic reticulum lumen] (R-HSA-2023664) 3x4Hyp-GalHyl-COL5A1(38-1838) [endoplasmic reticulum lumen] (R-HSA-2023553) GalHyl-COL5A1(38-1838) [endoplasmic reticulum lumen] (R-HSA-2023513) GlcGalHyl-COL5A1(38-1838) [endoplasmic reticulum lumen] (R-HSA-2023628) 3x4Hyp-3Hyp-GalHyl-COL5A1(38-1838) [endoplasmic reticulum lumen] (R-HSA-2023564) 3x4Hyp-3Hyp-GlcGalHyl-COL5A1(38-1838) [endoplasmic reticulum lumen] (R-HSA-2023647) COL5A1(38-1838) [endoplasmic reticulum lumen] (R-HSA-2022460) 3x4Hyp-COL5A1(38-1838) [endoplasmic reticulum lumen] (R-HSA-2022510) 3x4Hyp-3Hyp-COL5A1(38-1838) [endoplasmic reticulum lumen] (R-HSA-2022483) 3x4Hyp-5Hyl-COL5A1(38-1838) [endoplasmic reticulum lumen] (R-HSA-2022948) 3x4Hyp-3Hyp-5Hyl-COL5A1(38-1838) [endoplasmic reticulum lumen] (R-HSA-2022970) 5Hyl-COL5A1(38-1838) [endoplasmic reticulum lumen] (R-HSA-2022989) 3x4Hyp-GlcGalHyl-COL5A1(38-1838) [extracellular region] (R-HSA-2268653) COL5A1(38-1838) [extracellular region] (R-HSA-2268703) 3x4Hyp-5Hyl-COL5A1(38-1838) [extracellular region] (R-HSA-2268718) 3x4Hyp-GalHyl-COL5A1(38-1838) [extracellular region] (R-HSA-2268664) 3x4Hyp-3Hyp-COL5A1(38-1838) [extracellular region] (R-HSA-2268667) GalHyl-COL5A1(38-1838) [extracellular region] (R-HSA-2268629) 5Hyl-COL5A1(38-1838) [extracellular region] (R-HSA-2268644) 3x4Hyp-3Hyp-5Hyl-COL5A1(38-1838) [extracellular region] (R-HSA-2268663) 3x4Hyp-3Hyp-GalHyl-COL5A1(38-1838) [extracellular region] (R-HSA-2268662) GlcGalHyl-COL5A1(38-1838) [extracellular region] (R-HSA-2268625) 3x4Hyp-3Hyp-GlcGalHyl-COL5A1(38-1838) [extracellular region] (R-HSA-2268688) 3x4Hyp-COL5A1(38-1838) [extracellular region] (R-HSA-2268658) GalHyl-COL5A1(?-1838) [extracellular region] (R-HSA-2268878) 3x4Hyp-GlcGalHyl-COL5A1(?-1838) [extracellular region] (R-HSA-2268750) 3x4Hyp-3Hyp-GalHyl-COL5A1(?-1838) [extracellular region] (R-HSA-2268920) GlcGalHyl-COL5A1(?-1838) [extracellular region] (R-HSA-2268923) 3x4Hyp-5Hyl-COL5A1(?-1838) [extracellular region] (R-HSA-2268827) 3x4Hyp-COL5A1(?-1838) [extracellular region] (R-HSA-2268810) 3x4Hyp-3Hyp-COL5A1(?-1838) [extracellular region] (R-HSA-2268730) 3x4Hyp-3Hyp-5Hyl-COL5A1(?-1838) [extracellular region] (R-HSA-2268789) 5Hyl-COL5A1(?-1838) [extracellular region] (R-HSA-2268902) 3x4Hyp-GalHyl-COL5A1(?-1838) [extracellular region] (R-HSA-2268806) COL5A1(?-1838) [extracellular region] (R-HSA-2268801) 3x4Hyp-3Hyp-GlcGalHyl-COL5A1(?-1838) [extracellular region] (R-HSA-2268736) Collagen alpha-1(V) chain C-term fragment [extracellular region] (R-HSA-2470075) COL5A1(?-?) [extracellular region] (R-HSA-2470043) 3,4-Hyp 5-Hyl collagen alpha-1(V) chain C-term fragment [extracellular region] (R-HSA-2470136) 3x4Hyp-3Hyp-GlcGalHyl-COL5A1(?-?) [extracellular region] (R-HSA-2470169) 5-Gal-Hyl collagen alpha-1(V) chain C-term fragment [extracellular region] (R-HSA-2470174) 4-Hyp 5-Gal-Hyl collagen alpha-1(V) chain C-term fragment [extracellular region] (R-HSA-2470078) Glu-Gal-Hyl collagen alpha-1(V) chain C-term fragment [extracellular region] (R-HSA-2470044) 3,4-hydroxyprolyl collagen alpha-1(V) chain C-term fragment [extracellular region] (R-HSA-2470204) 3,4-Hyp 5-Gal-Hyl collagen alpha-1(V) chain C-term fragment [extracellular region] (R-HSA-2470172) 3x4Hyp-COL5A1(?-?) [extracellular region] (R-HSA-2470236) 3x4Hyp-5Hyl-COL5A1(?-?) [extracellular region] (R-HSA-2470108) GalHyl-COL5A1(?-?) [extracellular region] (R-HSA-2470205) 4-Hyp 5-Hyl collagen alpha-1(V) chain C-term fragment [extracellular region] (R-HSA-2470065) 5-hydroxylysyl collagen alpha-1(V) chain C-term fragment [extracellular region] (R-HSA-2470230) 3x4Hyp-GalHyl-COL5A1(?-?) [extracellular region] (R-HSA-2470036) 5Hyl-COL5A1(?-?) [extracellular region] (R-HSA-2470123) GlcGalHyl-COL5A1(?-?) [extracellular region] (R-HSA-2470088) 3,4-Hyp Glu-Gal-Hyl collagen alpha-1(V) chain C-term fragment [extracellular region] (R-HSA-2470153) 3x4Hyp-GlcGalHyl-COL5A1(?-?) [extracellular region] (R-HSA-2470190) 3x4Hyp-3Hyp-5Hyl-COL5A1(?-?) [extracellular region] (R-HSA-2470095) Glu-Gal-Hyl collagen alpha-1(V) chain [extracellular region] (R-HSA-2127312) 4-Hyp 5-Hyl collagen alpha-1(V) chain [extracellular region] (R-HSA-2127314) 4-Hyp Glu-Gal-Hyl collagen alpha-1(V) chain [extracellular region] (R-HSA-2127346) 3,4-Hyp 5-Hyl collagen alpha-1(V) chain [extracellular region] (R-HSA-2127396) 3,4-Hyp Glu-Gal-Hyl collagen alpha-1(V) chain [extracellular region] (R-HSA-2127412) 3,4-hydroxyprolyl collagen alpha-1(V) chain [extracellular region] (R-HSA-2127365) 4-hydroxyprolyl collagen alpha-1(V) chain [extracellular region] (R-HSA-2127429) 5-Gal-Hyl collagen alpha-1(V) chain [extracellular region] (R-HSA-2127397) 4-Hyp 5-Gal-Hyl collagen alpha-1(V) chain [extracellular region] (R-HSA-2127350) Collagen alpha-1(V) chain [extracellular region] (R-HSA-375058) 5-hydroxylysyl collagen alpha-1(V) chain [extracellular region] (R-HSA-2127433) 3,4-Hyp 5-Gal-Hyl collagen alpha-1(V) chain [extracellular region] (R-HSA-2127371) 3x4Hyp-3Hyp-GalHyl-COL5A1(?-?) [extracellular region] (R-HSA-2470116) 4-Hyp Glu-Gal-Hyl collagen alpha-1(V) chain C-term fragment [extracellular region] (R-HSA-2470112) 4-hydroxyprolyl collagen alpha-1(V) chain C-term fragment [extracellular region] (R-HSA-2470144) 3x4Hyp-3Hyp-COL5A1(?-?) [extracellular region] (R-HSA-2470050)	0.508	2

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