Collagen type IV networks bind integrins alpha1beta1, alpha2beta1

Stable Identifier
R-HSA-216040
Type
Reaction [binding]
Species
Homo sapiens
Compartment
extracellular region, plasma membrane
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Collagen type IV networks bind integrins alpha1beta1, alpha2beta1
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The collagen receptors integrin alpha2beta1 and alpha1beta1 bind collagen types I-IV (Tulla et al. 2001). Integrin alpha1beta1 binds to collagen type IV and VI with higher affinity than to types I-III, whereas alpha2beta1 has a higher affinity for collagen types I-III than for type IV (Tulla et al. 2001).

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Participant Of
hasEvent
Inferred From
Collagen type IV binds integrin alpha2beta1, alpha1beta1 (Homo sapiens)
Authored
Geiger, B  (2008-05-07)
Horwitz, AR  (2008-05-07)
Reviewed
Yamada, KM  (2008-05-07)
Humphries, MJ  (2008-05-07)
Hynes, R  (2008-05-07)
Created
Garapati, P V  (2008-03-11)