Reactome | Collagen type II binds integrin alpha10beta1

Collagen type II binds integrin alpha10beta1

Stable Identifier

R-HSA-216043

Type

Reaction [binding]

Species

Homo sapiens

Compartment

extracellular region, plasma membrane

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Collagen type II binds integrin alpha10beta1

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The integrin alpha10beta1 is a collagen type II-binding integrin on chondrocytes. This integrin is of great importance during chondrogenesis. alpha10 binds the collagen-II with its I domain displaying similar binding properties as alpha1 I domain.

Literature References

PubMed ID	Title	Journal	Year
15713743	Loss of alpha10beta1 integrin expression leads to moderate dysfunction of growth plate chondrocytes Bengtsson, T, Aszodi, A, Nicolae, C, Hunziker, EB, Lundgren-Akerlund, E, Fässler, R	J Cell Sci	2005