Collagen type II binds integrin alpha10beta1

Stable Identifier
R-HSA-216043
Type
Reaction [binding]
Species
Homo sapiens
Compartment
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The integrin alpha10beta1 is a collagen type II-binding integrin on chondrocytes. This integrin is of great importance during chondrogenesis. alpha10 binds the collagen-II with its I domain displaying similar binding properties as alpha1 I domain.

Literature References
PubMed ID Title Journal Year
15713743 Loss of alpha10beta1 integrin expression leads to moderate dysfunction of growth plate chondrocytes

Bengtsson, T, Aszodi, A, Nicolae, C, Hunziker, EB, Lundgren-Akerlund, E, Fässler, R

J Cell Sci 2005
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Orthologous Events
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