Interaction of integrin alpha8beta1 with Tenascin-C

Stable Identifier
R-HSA-216064
Type
Reaction [binding]
Species
Homo sapiens
Compartment
extracellular region, plasma membrane
ReviewStatus
5/5
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Interaction of integrin alpha8beta1 with Tenascin-C
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Tenascin-C (TN-C) and its isoforms are multidomain extracellular matrix (ECM) proteins that are believed to be involved in the regulation of stromal-epithelial interactions. Some of the interactions between TN-C and cells are mediated by integrins. Alpha8beta1 integrin interacts with the third FN type III repeats which contains an RGD sequence in tenascin-c.
Literature References
PubMed ID Title Journal Year
7541634 The integrin receptor alpha 8 beta 1 mediates interactions of embryonic chick motor and sensory neurons with tenascin-C

Chiquet, M, Backus, C, Kypta, R, Muller, U, Varnum-Finney, B, Venstrom, K, Reichardt, LF

Neuron 1995
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Orthologous Events
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Interaction of integrin alpha8beta1 with Tenascin-C (Gallus gallus)
Interaction of integrin alpha8beta1 with Tenascin-C (Mus musculus)
Interaction of integrin alpha8beta1 with Tenascin-C (Rattus norvegicus)
Interaction of integrin alpha8beta1 with Tenascin-C (Sus scrofa)
Interaction of integrin alpha8beta1 with Tenascin-C (Xenopus tropicalis)
Authored
Geiger, B  (2008-05-07)
Horwitz, AR  (2008-05-07)
Reviewed
Humphries, MJ  (2008-05-07)
Yamada, KM  (2008-05-07)
Hynes, R  (2008-05-07)
Created
Garapati, P V  (2008-03-11)
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