Disassembly of tight junctions

Stable Identifier
R-HSA-2160931
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
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Ubiquitination of RHOA by SMURF1 leads to disassembly of tight junctions, an important step in epithelial to mesenchymal transition.

Literature References
PubMed ID Title Journal Year
15761148 Regulation of the polarity protein Par6 by TGFbeta receptors controls epithelial cell plasticity

Ozdamar, B, Bose, R, Barrios-Rodiles, M, Wang, HR, Zhang, Y, Wrana, JL

Science 2005
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