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TACC3 [cytosol]
Stable Identifier
R-HSA-2160956
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Transforming acidic coiled-coil-containing protein 3, ERIC1
Locations in the PathwayBrowser for interactor UniProt:Q9GZM8 NDEL1
Expand all
Signal Transduction (Homo sapiens)
Signaling by NOTCH (Homo sapiens)
Signaling by NOTCH3 (Homo sapiens)
NOTCH3 Activation and Transmission of Signal to the Nucleus (Homo sapiens)
NICD3 binds to TACC3 (Homo sapiens)
TACC3 [cytosol] (Homo sapiens)
Signaling by NOTCH4 (Homo sapiens)
Negative regulation of NOTCH4 signaling (Homo sapiens)
NICD4 binds to TACC3 (Homo sapiens)
TACC3 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9Y6A5 TACC3
Gene Names
TACC3, ERIC1
Chain
initiator methionine:1, chain:2-838
Reference Genes
BioGPS Gene:10460 TACC3
COSMIC (genes):TACC3 TACC3
CTD Gene:10460 TACC3
dbSNP Gene:10460 TACC3
ENSEMBL:ENSG00000013810 TACC3
HGNC:11524 TACC3
KEGG Gene (Homo sapiens):10460 TACC3
Monarch:10460 TACC3
NCBI Gene:10460 TACC3
OMIM:605303 TACC3
UCSC:Q9Y6A5 TACC3
Reference Transcript
RefSeq:NM_006342.2 TACC3
RefSeq:XM_017007653.1 TACC3
Other Identifiers
0006350010
10111
10460
11718297_a_at
11746461_a_at
11763455_a_at
11763456_x_at
16964000
218308_at
22039
2714956
2714957
2714958
2714961
2714962
2714969
2714971
2714972
2714973
2714974
2714975
2714977
2714979
2714983
2714985
2714987
2714992
2714994
2714997
2714998
2714999
52238_s_at
5781
5LXN
5LXO
5ODS
5ODT
6050
8093500
A0A494BZT8
A_14_P128134
A_23_P212844
AAD25964
AAI06072
AAI11772
AF093543
AJ243997
BC106071
BC111771
C9JA91
C9JWI7
CAB010111
CAB53009
CCDS3352
E7EMT0
ENSG00000013810
ENSP00000326550
ENSP00000498361
ENST00000313288
ENST00000313288.8
ENST00000651472
EntrezGene:10460
EntrezGene:TACC3
F8WC55
g5454101_3p_at
GE58400
GO:0000226
GO:0000278
GO:0000922
GO:0003674
GO:0005515
GO:0005575
GO:0005622
GO:0005623
GO:0005737
GO:0005815
GO:0005819
GO:0005829
GO:0005856
GO:0007010
GO:0007049
GO:0007052
GO:0007059
GO:0007091
GO:0008150
GO:0008283
GO:0021987
GO:0043226
GO:0048856
GO:0051276
GO:0051301
GO:0060236
GO:0072686
GO:0140014
GO:1902850
HGNC:11524
HPA005781
HPA006050
HPA022039
ILMN_1724407
IPR007707
IPR039915
LRG_1367
LRG_1367t1
MIM:605303
NM_006342
NP_006333
PF05010
PH_hs_0005773
Q8IX09
TACC3
TACC3-201
TACC3-216
TC04000028.hg
UPI0000136869
XM_005247929
XM_005247930
XM_011513386
XM_017007653
XP_005247986
XP_005247987
XP_011511688
XP_016863142
Participant Of
hasComponent
NICD3:TACC3 [cytosol]
NICD4:TACC3 [cytosol]
input
NICD3 binds to TACC3
NICD4 binds to TACC3
Cross References
RefSeq
NP_006333.1
,
XP_016863142.1
OpenTargets
ENSG00000013810
GeneCards
Q9Y6A5
PRO
Q9Y6A5
PDB
5LXO
,
5ODS
,
5LXN
,
5ODT
Interactors (25)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q14008 CKAP5
1
CKAP5 [cytosol]
(R-HSA-377729)
0.739
7
UniProt:Q9NU19 TB22B
0.696
5
UniProt:Q2M2Z5 KIZ
0.696
5
UniProt:Q96Q77 CIB3
0.696
5
UniProt:A2AGT5
1
CKAP5 [cytosol]
(R-MMU-377729)
0.564
2
UniProt:A5D8V6 VPS37C
1
VPS37C [endosome membrane]
(R-HSA-184438)
0.556
3
UniProt:Q9BZE9 ASPSCR1
1
ASPSCR1 [cytoplasmic vesicle membrane]
(R-HSA-1449582)
0.556
3
UniProt:Q7Z614 SNX20
0.556
3
UniProt:Q9P270 SLAI2
0.527
3
UniProt:P09496 CLTA
6
CLTA [trans-Golgi network membrane]
(R-HSA-5333758)
CLTA [cytosol]
(R-HSA-8856817)
CLTA [lysosomal membrane]
(R-HSA-2980595)
CLTA [endolysosome membrane]
(R-HSA-8870825)
CLTA [clathrin-coated endocytic vesicle membrane]
(R-HSA-5138427)
CLTA [plasma membrane]
(R-HSA-2980611)
0.499
3
UniProt:Q9Y6A5 TACC3
1
TACC3 [cytosol]
(R-HSA-2160956)
0.488
2
UniProt:Q53EZ4 CEP55
0.488
2
UniProt:Q5VTR2 RNF20
1
RNF20 [nucleoplasm]
(R-HSA-5689011)
0.488
2
UniProt:Q8TD31-3 CCHCR1
0.488
2
UniProt:Q7Z3B4 NUP54
1
NUP54 [nuclear envelope]
(R-HSA-157724)
0.488
2
UniProt:Q86Y33-5 CDC20B
0.488
2
UniProt:Q00994 BEX3
1
NGFRAP1 [cytosol]
(R-HSA-194333)
0.488
2
UniProt:Q2WGJ6 KLH38
0.488
2
UniProt:Q9BXY8 BEX2
0.488
2
UniProt:Q07866-2 KLC1
0.488
2
UniProt:Q99988 GDF15
0.488
2
UniProt:Q8TC71 MIEAP
0.488
2
UniProt:Q53TS8 C2CD6
0.488
2
UniProt:Q99819 ARHGDIG
1
ARHGDIG [cytosol]
(R-HSA-195087)
0.488
2
UniProt:Q9GZM8 NDEL1
1
NDEL1 [cytosol]
(R-HSA-376258)
0.488
2
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