PGD2 is reduced to 11-epi-PGF2a by AKRIC3

Stable Identifier
R-HSA-2161614
Type
Reaction [transition]
Species
Homo sapiens
Compartment
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Aldo-keto reductase family 1 member C3 (AKR1C3) aka PGFS is the enzyme involved in NADPH-dependent prostaglandin D2 11-keto reductase activity of reducing prostaglandin D2 (PGD2) to 11-epi-Prostaglandin F2alpha (11-epi-PGF2a) (Liston & Roberts 1985, Koda et al. 2004).

Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
prostaglandin D2 11-ketoreductase activity of AKR1C3 [cytosol]
Physical Entity
Activity
Orthologous Events
Cross References
Rhea
Authored
Reviewed
Created
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