PGA2 is dehydrated to 15d-PGA2

Stable Identifier
R-HSA-2161668
Type
Reaction
Species
Homo sapiens
Compartment
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Summation

The non-enzymatic dehydration of prostaglandin A2 (PGA2) into 15-deoxy prostaglandin A2 (15d-PGA2) which occurs in mice (Petrova et al. 1999) is inferred in humans.

Literature References
PubMed ID Title Journal Year
10200320 Cyclopentenone prostaglandins suppress activation of microglia: down-regulation of inducible nitric-oxide synthase by 15-deoxy-Delta12,14-prostaglandin J2

Petrova, TV, Akama, KT, Van Eldik, LJ

Proc Natl Acad Sci U S A 1999
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