15S-HpETE is reduced to 15S-HETE by GPX1/2/4

Stable Identifier
R-HSA-2161791
Type
Reaction
Species
Homo sapiens
Compartment
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Glutathione peroxidases (GPXs) in human platelets (either GPX1, GPX2, or GPX4 are present in the cytosol) are involved in reducing 15S-hydroperoxyeicosatetraenoic acid (15S-HpETE) to 15S-hydroxyeicosatetraenoic acid (15S-HETE) (Hill et al. 1989).

Literature References
PubMed ID Title Journal Year
2501828 Role of glutathione and glutathione peroxidase in human platelet arachidonic acid metabolism

Hill, TD, White, JG, Rao, GH

Prostaglandins 1989
Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
glutathione peroxidase activity of GPX1/2/4 [cytosol]
Physical Entity
Activity
Orthologous Events
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Created
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