HXA3/B3 is hydrolysed to TrXA3/B3 by HXEH

Stable Identifier
R-HSA-2161949
Type
Reaction [transition]
Species
Homo sapiens
Compartment
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The epoxy moiety of hepoxilin A3 (HXA3) and B3 (HXB3) is labile and can be hydrolysed either by a hepoxilin specific epoxide hydrolase (HXEH) or in acidic aqueous solution to form the corresponding diol metabolites trioxilin A3 (TrXA3) and B3 (TrXB3) (Anton et al. 1995, Anton et al. 1998, Pace-Asciak et al. 1983, Pace-Asciak & Lee 1989).

Literature References
Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
hepoxilin-epoxide hydrolase activity of HXEH [cytosol]
Physical Entity
Activity
Authored
Reviewed
Created