There will be a maintenance on OICR IT systems starting Friday Dec 15 at 6PM EST until midnight Sunday Dec 17; Reactome will be affected by this downtime

Service under maintenance from Friday Dec 15 at 6PM EST until midnight Sunday Dec 17

LTA4 is converted to EXA4 by ALOX15

Stable Identifier
R-HSA-2162019
Type
Reaction
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

Analogous to arachidonate 5-lipoxygenase (ALOX5) biosynthesis of leukotriene A4 (LTA4), arachidonate 15-lipoxygenase (ALOX15) can form an epoxide across C-14 and C-15 to form 14,15-LTA4 aka eoxin A4 (EXA4) (Feltenmark et al. 2008, Claesson et al. 2008).

Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
eoxin A4 synthase activity of ALOX15:Fe2+ [cytosol]
Physical Entity
Activity
Orthologous Events