carbovir monophosphate + ATP => carbovir diphosphate + ADP

Stable Identifier
R-HSA-2162092
Type
Reaction [transition]
Species
Homo sapiens
Compartment
Synonyms
Phosphorylation of carbovir monophosphate
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Cytosolic GUK1 (guanylate kinase 1) catalyzes the reaction of carbovir monophosphate and ATP to form carbovir diphosphate and ADP. The activity of human GUK1 is inferred from that of the corresponding pig protein (Miller et al. 1992).

Literature References
PubMed ID Title Journal Year
1383219 Phosphorylation of carbovir enantiomers by cellular enzymes determines the stereoselectivity of antiviral activity

Miller, WH, Daluge, SM, Garvey, EP, Hopkins, S, Reardon, JE, Boyd, FL, Miller, RL

J Biol Chem 1992
Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
nucleoside monophosphate kinase activity of GUK1 [cytosol]
Physical Entity
Activity
Inferred From
Authored
Reviewed
Created