carbovir diphosphate + ATP => carbovir triphosphate + ADP

Stable Identifier
R-HSA-2162096
Type
Reaction [transition]
Species
Homo sapiens
Compartment
Synonyms
Phosphorylation of carbovir diphosphate
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Cytosolic PCK1 (phosphoenolpyruvate carboxykinase 1) catalyzes the reaction of carbovir diphosphate and ATP to form carbovir triphosphate and ADP. The activity of human PCK1 and relative inactivity of human nucleoside diphosphate kinase are inferred from the properties of the purified rat and bovine enzymes in vitro (Miller et al. 1992).

Literature References
PubMed ID Title Journal Year
1383219 Phosphorylation of carbovir enantiomers by cellular enzymes determines the stereoselectivity of antiviral activity

Miller, WH, Daluge, SM, Garvey, EP, Hopkins, S, Reardon, JE, Boyd, FL, Miller, RL

J Biol Chem 1992
Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
nucleoside diphosphate kinase activity of PCK1 [cytosol]
Physical Entity
Activity
Inferred From
Authored
Reviewed
Created