Reactome | COQ3 methylates DeMQ10H2

COQ3 methylates DeMQ10H2

Stable Identifier

R-HSA-2162186

Type

Reaction [transition]

Species

Homo sapiens

Compartment

mitochondrial matrix

Synonyms

DeMQ10H2 is methylated to Q10H2 by COQ3

ReviewStatus

5/5

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Mitochondrial COQ3 is an O-methyltransferase required in the reaction to convert 3-demethylubiquinol-10 (DeMQ10H2) to ubiquinol-10 (Q10H2) (Jonassen & Clarke 2000).

Literature References

PubMed ID	Title	Journal	Year
26251450	Structural and biochemical studies reveal UbiG/Coq3 as a class of novel membrane-binding proteins Zhang, X, Zhu, Y, Niu, L, Wu, B, Wang, J, Li, X, Fan, X, Teng, M	Biochem J	2015
10777520	Isolation and functional expression of human COQ3, a gene encoding a methyltransferase required for ubiquinone biosynthesis Jonassen, T, Clarke, CF	J Biol Chem	2000