Recruitment of PLK1 to phosphorylated GORASP1 (GRASP65)

Stable Identifier
R-HSA-2172194
Type
Reaction [binding]
Species
Homo sapiens
Compartment
Golgi membrane, cytosol
ReviewStatus
5/5
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Recruitment of PLK1 to phosphorylated GORASP1 (GRASP65)
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Phosphorylation of GORASP1 (GRASP65) by cyclin B-associated CDK1 creates a docking site for PLK1. PLK1 is also able to bind to CDK1-phosphorylated RAB1, but not to CDK1-phosphorylated GOLGA2 (Preisinger et al. 2005).
Literature References
PubMed ID Title Journal Year
15678101 Plk1 docking to GRASP65 phosphorylated by Cdk1 suggests a mechanism for Golgi checkpoint signalling

Wind, M, Barr, FA, Korner, R, Kopajtich, R, Lehmann, WD, Preisinger, C

EMBO J 2005
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Input
Output
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as an event of
Inferred From
PLK1 binds phosphorylated Gorasp1 (Homo sapiens)
Authored
Orlic-Milacic, M  (2012-07-20)
Reviewed
Wang, Y  (2012-08-19)
Malhotra, V  (2012-08-15)
Colanzi, A  (2012-08-21)
Created
Orlic-Milacic, M  (2012-03-29)
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