Reactome | JUNB [nucleoplasm]

JUNB [nucleoplasm]

Stable Identifier

R-HSA-2186795

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

Transcription factor jun-B

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:P17275 JUNB

Gene Names

JUNB

Chain

chain:1-347

Reference Genes

BioGPS Gene:3726 JUNB

COSMIC (genes):JUNB JUNB

CTD Gene:3726 JUNB

dbSNP Gene:3726 JUNB

ENSEMBL:ENSG00000171223 JUNB

HGNC:6205 JUNB

KEGG Gene (Homo sapiens):3726 JUNB

Monarch:3726 JUNB

NCBI Gene:3726 JUNB

OMIM:165161 JUNB

Reference Transcript

RefSeq:NM_002229.2 JUNB

Other Identifiers

0001400746

11715673_x_at

16858710

201473_at

2049_s_at

32786_at

3726

3821895

3821896

3821897

3821898

3821899

8026047

A_14_P128210

A_23_P4821

A_24_P241815

GE511331

GE86615

GO:0000003

GO:0000785

GO:0000977

GO:0000978

GO:0000981

GO:0001228

GO:0001570

GO:0001649

GO:0001701

GO:0001829

GO:0002376

GO:0003674

GO:0003677

GO:0003700

GO:0005515

GO:0005575

GO:0005622

GO:0005634

GO:0005654

GO:0005667

GO:0005694

GO:0006355

GO:0006357

GO:0007049

GO:0007165

GO:0008134

GO:0008150

GO:0008283

GO:0009058

GO:0009790

GO:0009987

GO:0019221

GO:0030154

GO:0030316

GO:0032991

GO:0033687

GO:0034641

GO:0035976

GO:0042127

GO:0043226

GO:0045597

GO:0045944

GO:0046697

GO:0048646

GO:0048856

GO:0051726

GO:0060136

GO:0060716

GO:0071277

GO:1990837

HMNXSV003027341

ILMN_1777184

ILMN_2086077

PH_hs_0030027

TC19000228.hg

TC19001995.hg

U20734_s_at

X51345_at

g4504808_3p_s_at

Participates

as a member of

as an output of

SMAD2/3:SMAD4 complex positively regulates JUNB transcription (Homo sapiens)

Cross References

RefSeq

NP_002220.1

Target Pathogen

5b354852be737e166372ebe6

OpenTargets

ENSG00000171223

HPA

ENSG00000171223-JUNB

GeneCards

P17275

Ensembl

ENST00000302754, ENSP00000303315, ENSG00000171223

PRO

P17275

Interactors (16)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q16520 BATF	1	BATF [nucleoplasm] (R-HSA-6789925)	0.955	30
UniProt:P01100 FOS	2	p-T325,T331,S362,S374-FOS [nucleoplasm] (R-HSA-450283) FOS [nucleoplasm] (R-HSA-450216)	0.902	9
UniProt:P15408 FOSL2			0.858	8
UniProt:P15407 FOSL1	1	FOSL1 [nucleoplasm] (R-HSA-9620405)	0.743	7
UniProt:P15336 ATF2	2	p-T69,T71-ATF2 [nucleoplasm] (R-HSA-450243) ATF2 [nucleoplasm] (R-HSA-450336)	0.693	3
UniProt:P18847 ATF3	1	ATF3 [nucleoplasm] (R-HSA-535543)	0.688	4
UniProt:P53539 FOSB	1	FOSB [nucleoplasm] (R-HSA-9009922)	0.666	6
UniProt:Q6FG41 Q6FG41			0.601	4
UniProt:Q9NR55 BATF3			0.59	3
UniProt:P22607 FGFR3	40	FGFR3 K650N [plasma membrane] (R-HSA-1614406) FGFR3 K650T [plasma membrane] (R-HSA-1614411) FGFR3 K650M [plasma membrane] (R-HSA-1614402) FGFR3 K650Q [plasma membrane] (R-HSA-1614410) FGFR3 A391E [plasma membrane] (R-HSA-1614390) FGFR3 K650E [plasma membrane] (R-HSA-1614400) FGFR3 G380R [plasma membrane] (R-HSA-1614398) FGFR3 G382D [plasma membrane] (R-HSA-2018740) FGFR3 795fs139 [plasma membrane] (R-HSA-1614387) FGFR3 [plasma membrane] (R-HSA-2038357) FGFR3 S371C [plasma membrane] (R-HSA-1614421) FGFR3 Y373C [plasma membrane] (R-HSA-1614424) FGFR3 G370C [plasma membrane] (R-HSA-1614394) FGFR3 R248C [plasma membrane] (R-HSA-1614419) p-6Y-FGFR3 S371C [plasma membrane] (R-HSA-2011886) p-6Y-FGFR3 G370C [plasma membrane] (R-HSA-2011883) p-6Y-FGFR3 Y373C [plasma membrane] (R-HSA-2011889) p-6Y-FGFR3 795fs139 [plasma membrane] (R-HSA-2038360) p-6Y-FGFR3 R248C [plasma membrane] (R-HSA-2011884) pY-FGFR3 [plasma membrane] (R-HSA-2038368) p-6Y-FGFR3 K650Q [plasma membrane] (R-HSA-2032962) p-6Y-FGFR3 K650N [plasma membrane] (R-HSA-2032961) p-6Y-FGFR3 K650E [plasma membrane] (R-HSA-2032952) p-6Y-FGFR3 K650M [plasma membrane] (R-HSA-2032959) p-6Y-FGFR3 G380R [plasma membrane] (R-HSA-2032946) p-6Y-FGFR3 G382D [plasma membrane] (R-HSA-2032950) p-6Y-FGFR3 K650T [plasma membrane] (R-HSA-2032966) p-6Y-FGFR3 A391E [plasma membrane] (R-HSA-2065835) p-4Y FGFR3(23-760)-TACC3(612-838) fusion [plasma membrane] (R-HSA-8853147) p-4Y FGFR3(23-760)-TACC3(647-838) fusion [plasma membrane] (R-HSA-8853155) p-4Y FGFR3(23-793)-TACC3(143-838) fusion [plasma membrane] (R-HSA-8853145) p-4Y FGFR3(23-758)-TACC3(549-838) fusion [plasma membrane] (R-HSA-8853129) p-4Y FGFR3(23-758)-TACC3(649-838) fusion [plasma membrane] (R-HSA-8853151) p-4Y FGFR3(23-760)-BAIAP2L1(18-522) fusion [plasma membrane] (R-HSA-8853128) FGFR3(23-760)-TACC3(612-838) fusion [plasma membrane] (R-HSA-8853144) FGFR3(23-760)-BAIAP2L1(18-522) fusion [plasma membrane] (R-HSA-8853131) FGFR3(23-793)-TACC3(143-838) fusion [plasma membrane] (R-HSA-8853152) FGFR3(23-758)-TACC3(549-838) fusion [plasma membrane] (R-HSA-8853124) FGFR3(23-758)-TACC3(649-838) fusion [plasma membrane] (R-HSA-8853125) FGFR3(23-760)-TACC3(647-838) fusion [plasma membrane] (R-HSA-8853127)	0.556	3
UniProt:P28329-3 P283293			0.556	3
UniProt:Q8N1L9 BATF2			0.543	3
UniProt:P05412 JUN	4	p-S63,S73-JUN [nucleoplasm] (R-HSA-450237) JUN [nucleoplasm] (R-HSA-450250) JUN [cytosol] (R-HSA-168194) p-S63,S73-JUN [cytosol] (R-HSA-8868682)	0.527	2
UniProt:Q86XI8 ZSWM9			0.524	2
UniProt:P56279 TCL1A			0.524	2
IntAct:EBI-10046032 CCR4			0.499	4

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