2xADPRib-p-S423,S425-SMAD3 [nucleoplasm]

Stable Identifier
R-HSA-2187326
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
Synonyms
PAR,p-2S-SMAD3, ADP-D-ribosyl,phospho-SMAD 3, PARylated, phospho-SMAD3
2xADPRib-p-S423,S425-SMAD3 [nucleoplasm] icon
Locations in the PathwayBrowser
External Reference Information
External Reference
Gene Names
SMAD3, MADH3
Chain
initiator methionine:, chain:2-425
Other Identifiers
11718265_a_at
11718266_s_at
11726549_a_at
11751185_a_at
11754091_s_at
1433_g_at
1454_at
1950_s_at
205396_PM_at
205396_at
205397_PM_x_at
205397_x_at
205398_PM_s_at
205398_s_at
218284_PM_at
218284_at
3598960
3598961
3598977
3598984
3598992
3598993
3598994
3598995
3598997
3598999
3599014
3599016
3599023
3599028
3599029
3599030
3599031
3599032
3599033
3599034
3599035
3599036
3599037
3599038
3599039
3599040
3599041
3599042
38944_at
4088
44841_at
44986_s_at
51059_at
58763_at
65983_at
7984364
A_14_P107358
A_23_P48936
GE56446
GE79350
GO:0000122
GO:0000165
GO:0000785
GO:0000976
GO:0000977
GO:0000978
GO:0000981
GO:0000987
GO:0001217
GO:0001222
GO:0001223
GO:0001228
GO:0001501
GO:0001649
GO:0001657
GO:0001666
GO:0001701
GO:0001707
GO:0001756
GO:0001889
GO:0001947
GO:0002076
GO:0002376
GO:0002520
GO:0003012
GO:0003013
GO:0003677
GO:0003682
GO:0003690
GO:0003700
GO:0005160
GO:0005515
GO:0005518
GO:0005634
GO:0005635
GO:0005637
GO:0005654
GO:0005667
GO:0005694
GO:0005737
GO:0005829
GO:0005886
GO:0006351
GO:0006355
GO:0006357
GO:0006886
GO:0006913
GO:0006919
GO:0006954
GO:0006955
GO:0007010
GO:0007155
GO:0007179
GO:0007254
GO:0007369
GO:0007492
GO:0008013
GO:0008270
GO:0008285
GO:0009653
GO:0009880
GO:0010628
GO:0010629
GO:0010718
GO:0012501
GO:0016202
GO:0016922
GO:0017015
GO:0017151
GO:0019899
GO:0019901
GO:0019902
GO:0023019
GO:0023052
GO:0030154
GO:0030163
GO:0030198
GO:0030308
GO:0030325
GO:0030335
GO:0030501
GO:0030878
GO:0031047
GO:0031053
GO:0031490
GO:0031625
GO:0031962
GO:0032332
GO:0032731
GO:0032810
GO:0032909
GO:0032916
GO:0032924
GO:0033689
GO:0034330
GO:0035259
GO:0038092
GO:0042060
GO:0042110
GO:0042177
GO:0042307
GO:0042802
GO:0042803
GO:0043066
GO:0043130
GO:0043226
GO:0043235
GO:0043425
GO:0043565
GO:0045216
GO:0045429
GO:0045599
GO:0045668
GO:0045893
GO:0045944
GO:0046872
GO:0048340
GO:0048589
GO:0048617
GO:0048701
GO:0048856
GO:0048870
GO:0050678
GO:0050728
GO:0050776
GO:0050821
GO:0050927
GO:0051091
GO:0051481
GO:0051496
GO:0051894
GO:0060039
GO:0060290
GO:0060395
GO:0061045
GO:0061629
GO:0061767
GO:0070306
GO:0070410
GO:0070411
GO:0070412
GO:0071141
GO:0071144
GO:0071333
GO:0071560
GO:0090263
GO:0097191
GO:0098586
GO:0140110
GO:0140297
GO:1901203
GO:1902893
GO:1902894
GO:1902895
GO:1903243
GO:1990776
GO:1990841
HMNXSV003022522
Hs.211578.0.S3_3p_at
ILMN_1682738
PH_hs_0032513
PH_hs_0039929
TC15000622.hg
TC15002251.hg
U68019_at
g1673576_3p_s_at
g5174512_3p_s_at
g7661691_3p_at
Participates
Other forms of this molecule
Inferred To
Modified Residues
Name
O-phospho-L-serine at 423
Coordinate
423
PsiMod Name
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-serine at 425
Coordinate
425
PsiMod Name
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
L-glutamyl-5-poly(ADP-ribose) at 50
Coordinate
50
PsiMod Name
PsiMod Definition
A protein modification that effectively converts an L-glutamic acid residue to L-glutamyl-5-poly(ADP-ribose).
Name
L-glutamyl-5-poly(ADP-ribose) at 52
Coordinate
52
PsiMod Name
PsiMod Definition
A protein modification that effectively converts an L-glutamic acid residue to L-glutamyl-5-poly(ADP-ribose).
Interactors (71)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:Q13485 SMAD4  20 0.98 35
 UniProt:P12755 SKI  1 0.837 11
 UniProt:O95405 ZFYVE9      0.821 7
 UniProt:Q9H2G9 BLZF1  1 0.805 9
 UniProt:Q9H0M0 WWP1  1 0.805 9
 UniProt:Q9HAU4 SMURF2  2 0.799 8
 UniProt:O00308 WWP2  1 0.779 7
 UniProt:P50222 MEOX2      0.718 6
 UniProt:Q13573 SNW1  1 0.69 5
 UniProt:Q15796 SMAD2  20 0.678 3
 UniProt:O75593 FOXH1  1 0.675 4
 UniProt:Q9Y2U8 LEMD3  4 0.669 4
 UniProt:O43524 FOXO3  11 0.667 5
 UniProt:Q08117 TLE5  1 0.666 4
 UniProt:Q8N5R6 CCD33      0.666 4
 UniProt:P84022 SMAD3  20 0.656 3
 UniProt:Q64729  3 0.576 6
 UniProt:Q9BZ29 DOCK9  1 0.576 3
 UniProt:Q93009 USP7  2 0.573 2
 UniProt:P10070 GLI2  11 0.558 4
 UniProt:P46934-3 NEDD4      0.556 3
 UniProt:P17612 PRKACA  4 0.556 3
 UniProt:Q06481-5 APLP2      0.556 3
 UniProt:P48730-2 CSNK1D      0.556 3
 UniProt:P29466-3 CASP1      0.556 3
 UniProt:Q86YD7 F90A1      0.556 3
 UniProt:Q8N684-3 CPSF7      0.556 3
 UniProt:P0C264 SBK3      0.556 3
 UniProt:Q8IXK0-5 PHC2      0.556 3
 UniProt:E9PSE9 E9PSE9      0.556 3
 UniProt:P27986-2 PIK3R1      0.556 3
 IntAct:EBI-16439879 CCSB ORF ID      0.556 3
 UniProt:Q08117-2 TLE5      0.556 3
 UniProt:O43186 CRX      0.556 3
 UniProt:Q15583 TGIF1  1 0.556 3
 UniProt:Q96PZ7 CSMD1      0.556 3
 UniProt:Q8WXH2 JPH3      0.556 3
 UniProt:Q8WW24 TEKT4      0.556 3
 UniProt:Q8N684 CPSF7  2 0.556 3
 UniProt:P05067 APP  20 0.556 3
 UniProt:Q9UQM7 CAMK2A  6 0.556 3
 UniProt:Q8IXK0 PHC2  1 0.556 3
 IntAct:EBI-10171584 80125      0.556 3
 UniProt:Q6NX45 ZNF774  1 0.556 3
 UniProt:P20618 PSMB1  7 0.556 3
 UniProt:P15822 ZEP1      0.553 2
 UniProt:P06428 VE6      0.547 2
 UniProt:O15397 IPO8  2 0.544 2
 UniProt:Q99836 MYD88  8 0.543 3
 UniProt:Q13501 SQSTM1  7 0.543 3
 UniProt:Q9GZZ8 LACRT      0.527 2
 UniProt:P51141 Dvl1  4 0.527 2
 UniProt:Q9NYA4 MTMR4  2 0.524 2
 UniProt:P98082 DAB2  3 0.524 3
 UniProt:Q99814 EPAS1 (HIF2A)  5 0.519 2
 UniProt:Q9BZL4 PP12C      0.508 2
 UniProt:Q9H2X0 CHRD      0.508 2
 UniProt:Q96EP0 RNF31  1 0.508 2
 UniProt:Q9Y3Q8 T22D4      0.508 2
 UniProt:Q5D1E8 ZC3H12A  1 0.508 2
 UniProt:Q16822 PCK2  1 0.508 2
 UniProt:Q9BYW2 SETD2  1 0.508 2
 UniProt:Q01543 FLI1  1 0.508 3
 UniProt:P17844 DDX5  4 0.499 2
 UniProt:Q05066 SRY  1 0.499 3
 UniProt:P06930 VE6      0.488 2
 UniProt:P36801 VE6      0.488 2
 UniProt:P23142 FBLN1  1 0.488 2
 UniProt:Q93062-3 RBPMS      0.488 2
 UniProt:Q16665 HIF1A  7 0.463 6
 UniProt:Q9NZH6 IL37  6 0.463 2
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