Reactome | VPS39 [endosome membrane]

VPS39 [endosome membrane]

Stable Identifier

R-HSA-2197806

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

endosome membrane

Synonyms

Vam6/Vps39-like protein, VPS39_HUMAN

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q96JC1 VPS39

Gene Names

VPS39, KIAA0770, TLP, VAM6

Chain

chain:1-886

Reference Genes

BioGPS Gene:23339 VPS39

COSMIC (genes):VPS39 VPS39

CTD Gene:23339 VPS39

dbSNP Gene:23339 VPS39

ENSEMBL:ENSG00000166887 VPS39

HGNC:20593 VPS39

KEGG:hsa:23339 VPS39

Monarch:23339 VPS39

NCBI Gene:23339 VPS39

OMIM:612188 VPS39

UCSC:Q96JC1 VPS39

Reference Transcript

Participates

as a component of

HOPS Complex [endosome membrane] (Homo sapiens)

Cross References

RefSeq

NP_001288067.1, NP_056104.2

ENSEMBL

ENSP00000326534, ENST00000348544, ENST00000318006, ENSP00000335193, ENSG00000166887

OpenTargets

ENSG00000166887

GeneCards

VPS39

HPA

ENSG00000166887-VPS39

PRO

Q96JC1

Pharos - Targets

Q96JC1

HMDB Protein

HMDBP14485

PDB

6ZE9

Interactors (2)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P0DTC3 3a	9	O-glycosyl 3a [virion membrane] (R-COV-9694395) O-glycosyl 3a [endocytic vesicle membrane] (R-COV-9694729) O-glycosyl 3a [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-COV-9694386) GalNAc-O-3a [endoplasmic reticulum-Golgi intermediate compartment] (R-COV-9694658) 3a [endoplasmic reticulum-Golgi intermediate compartment] (R-COV-9694716) 3a [endoplasmic reticulum lumen] (R-COV-9694584) O-glycosyl 3a [endolysosome membrane] (R-COV-9754541) O-glycosyl 3a [plasma membrane] (R-COV-9694433) O-glycosyl 3a [extracellular region] (R-COV-9694387)	0.956	19
UniProt:P51149 RAB7A	7	RAB7A [secretory granule membrane] (R-HSA-6804969) RAB7A [plasma membrane] (R-HSA-6804990) RAB7A [cytosol] (R-HSA-8870415) RAB7A [phagocytic vesicle membrane] (R-HSA-9636586) RAB7A [lysosomal membrane] (R-HSA-2213231) GGC-RAB7A [cytosol] (R-HSA-8870438) GGC-RAB7A [lysosomal membrane] (R-HSA-8877454)	0.499	2

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