TLR4 [endosome membrane]

Stable Identifier
R-HSA-2201285
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
endosome membrane
Icon
TLR4 [endosome membrane] icon
TLR4 [endosome membrane] icon
Locations in the PathwayBrowser
Expand all
External Reference Information
External Reference
UniProt:O00206 TLR4
Gene Names
TLR4
Chain
signal peptide:1-23, chain:24-839
Reference Genes
BioGPS Gene:7099 TLR4
COSMIC (genes):TLR4 TLR4
CTD Gene:7099 TLR4
dbSNP Gene:7099 TLR4
ENSEMBL:ENSG00000136869 TLR4
ENSEMBL:ENSG00000136869.16 TLR4
HGNC:11850 TLR4
KEGG Gene (Homo sapiens):7099 TLR4
Monarch:7099 TLR4
NCBI Gene:7099 TLR4
OMIM:603030 TLR4
UCSC:O00206 TLR4
Reference Transcript
Other Identifiers
11743196_a_at
11743197_at
11747518_a_at
1552798_PM_a_at
1552798_a_at
17088527
221060_PM_s_at
221060_s_at
224341_PM_x_at
224341_x_at
232068_PM_s_at
232068_s_at
240948_PM_at
240948_at
3186967
3186968
3186969
3186971
3186972
3186973
3186974
3186976
3186977
3186978
3186979
3186980
3186981
3186982
3186983
3186984
3186985
3186986
3186987
3186988
3186989
3186990
3186991
3186992
3186993
3186994
3186995
43219_at
7099
75770_at
76813_i_at
76817_r_at
8157524
A_14_P202106
A_23_P60306
A_24_P69538
A_24_P868313
A_32_P66881
GE470555
GE59576
GO:0001530
GO:0001540
GO:0001726
GO:0001875
GO:0001891
GO:0002218
GO:0002224
GO:0002246
GO:0002322
GO:0002376
GO:0002537
GO:0002730
GO:0002755
GO:0003824
GO:0004888
GO:0005102
GO:0005515
GO:0005737
GO:0005768
GO:0005769
GO:0005794
GO:0005886
GO:0006351
GO:0006355
GO:0006809
GO:0006909
GO:0006954
GO:0006955
GO:0007165
GO:0007249
GO:0007252
GO:0007254
GO:0008289
GO:0009617
GO:0009897
GO:0009986
GO:0010008
GO:0010467
GO:0010572
GO:0010628
GO:0012501
GO:0014002
GO:0014004
GO:0014911
GO:0016020
GO:0016046
GO:0016192
GO:0016787
GO:0022008
GO:0022600
GO:0023052
GO:0030154
GO:0030890
GO:0031410
GO:0031663
GO:0032496
GO:0032497
GO:0032689
GO:0032700
GO:0032707
GO:0032715
GO:0032720
GO:0032722
GO:0032727
GO:0032728
GO:0032729
GO:0032731
GO:0032732
GO:0032733
GO:0032735
GO:0032755
GO:0032757
GO:0032760
GO:0032874
GO:0034142
GO:0035666
GO:0036120
GO:0036211
GO:0038023
GO:0042060
GO:0042088
GO:0042100
GO:0042116
GO:0042742
GO:0042802
GO:0042995
GO:0043032
GO:0043123
GO:0043226
GO:0043235
GO:0043406
GO:0045087
GO:0045342
GO:0045348
GO:0045429
GO:0045671
GO:0045944
GO:0046330
GO:0046651
GO:0046696
GO:0046982
GO:0048471
GO:0048661
GO:0048856
GO:0048870
GO:0050135
GO:0050671
GO:0050727
GO:0050729
GO:0050829
GO:0051092
GO:0051403
GO:0051770
GO:0060089
GO:0060729
GO:0060907
GO:0061809
GO:0065003
GO:0070371
GO:0070373
GO:0070374
GO:0070427
GO:0070430
GO:0070431
GO:0070434
GO:0071222
GO:0071223
GO:0071260
GO:0071346
GO:0098542
GO:0120163
GO:0140052
GO:1900017
GO:1900227
GO:1901224
GO:1903428
GO:1903974
GO:1904466
GO:1904646
GO:2000343
GO:2001238
HMNXSV003033006
Hs.177864.0.A1_3p_at
Hs2.159239.2.S1_3p_s_at
ILMN_1706217
PH_hs_0030838
TC09000601.hg
TC09002219.hg
U93091_at
g2429102_3p_s_at
g4507532_3p_s_at
Participates
as a component of
Other forms of this molecule
2xN4GlycoAsn-TLR4 [plasma membrane]
Inferred To
TLR4 [endosome membrane] (Bos taurus)
TLR4 [endosome membrane] (Canis familiaris)
TLR4 [endosome membrane] (Danio rerio)
TLR4 [endosome membrane] (Gallus gallus)
TLR4 [endosome membrane] (Sus scrofa)
Ghost homologue of TLR4 [endosome membrane] (Xenopus tropicalis)
Tlr4 [endosome membrane] (Mus musculus)
Tlr4 [endosome membrane] (Rattus norvegicus)
Cross References
RefSeq
Guide to Pharmacology - Targets
OpenTargets
ZINC - Substances
ZINC target
PRO
PDB
ZINC - Investigational
HPA
GeneCards
Ensembl
Pharos - Targets
ZINC - Predictions - Purchasable
Orphanet
HMDB Protein
Interactors (12)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:P58753 TIRAP  2 0.807 6
 UniProt:Q99836 MYD88  8 0.758 4
 UniProt:Q9Y6Y9 LY96  3 0.743 7
 UniProt:O00206 TLR4  2 0.692 3
 UniProt:Q9NPH5 NOX4  2 0.683 4
 UniProt:Q86XR7 TICAM2  3 0.678 3
 UniProt:P09429 HMGB1  5 0.604 3
 UniProt:P11226 MBL2  1 0.558 2
 UniProt:Q9Y336 SIGLEC9  2 0.544 2
 UniProt:O15389 SIGLEC5  4 0.544 2
 UniProt:O43699-3 SIGLEC6      0.544 2
 UniProt:Q9Y2C9 TLR6  1 0.499 2
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