PDPK1 binds PIP2

Stable Identifier
R-HSA-2219524
Type
Reaction [binding]
Species
Homo sapiens
Compartment
ReviewStatus
5/5
Locations in the PathwayBrowser
General
SVG |   | PPTX  | SBGN
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
PDPK1 (PDK1) possesses low affinity for PIP2, so small amounts of PDPK1 are always present at the membrane, in the absence of PI3K activity (Currie et al. 1999).
Literature References
PubMed ID Title Journal Year
9895304 Role of phosphatidylinositol 3,4,5-trisphosphate in regulating the activity and localization of 3-phosphoinositide-dependent protein kinase-1

Alessi, DR, Cohen, P, Downes, CP, Casamayor, A, Lucocq, J, Currie, RA, Deak, M, Gray, A, Walker, KS

Biochem J 1999
Participants
Participates
Orthologous Events
Authored
Reviewed
Created
Cite Us!