NOTCH1 PEST domain mutants stimulate HES5 transcription

Stable Identifier
R-HSA-2220966
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
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NICD1 PEST domain mutants are expected to stimulate HES5 transcription in a similar manner to wild-type NICD1 (Arnett et al. 2010).

Literature References
PubMed ID Title Journal Year
20972443 Structural and mechanistic insights into cooperative assembly of dimeric Notch transcription complexes

Arnett, KL, Hass, M, McArthur, DG, Ilagan, MXG, Aster, JC, Kopan, R, Blacklow, SC

Nat Struct Mol Biol 2010
Participants
Participant Of
This event is regulated
Normal reaction
Disease
Name Identifier Synonyms
T-cell leukemia 715
cancer 162 malignant tumor, malignant neoplasm, primary cancer
Authored
Reviewed
Created