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COL1A1(162-1464) [extracellular region]
Stable Identifier
R-HSA-2268848
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
extracellular region
Synonyms
Collagen alpha-1(I) -N propeptide
Locations in the PathwayBrowser
Expand all
Extracellular matrix organization (Homo sapiens)
Collagen formation (Homo sapiens)
Collagen biosynthesis and modifying enzymes (Homo sapiens)
Removal of fibrillar collagen C-propeptides (Homo sapiens)
Fibrillar procollagens -N [extracellular region] (Homo sapiens)
Procollagen type I -N [extracellular region] (Homo sapiens)
Alpha-1(I) -N propeptides [extracellular region] (Homo sapiens)
COL1A1(162-1464) [extracellular region] (Homo sapiens)
Removal of fibrillar collagen N-propeptides (Homo sapiens)
Fibrillar procollagens -N [extracellular region] (Homo sapiens)
Procollagen type I -N [extracellular region] (Homo sapiens)
Alpha-1(I) -N propeptides [extracellular region] (Homo sapiens)
COL1A1(162-1464) [extracellular region] (Homo sapiens)
External Reference Information
External Reference
UniProt:P02452 COL1A1
Gene Names
COL1A1
Chain
signal peptide:1-22, propeptide:23-161, chain:162-1218, propeptide:1219-1464
Reference Genes
BioGPS Gene:1277 COL1A1
COSMIC (genes):COL1A1 COL1A1
CTD Gene:1277 COL1A1
dbSNP Gene:1277 COL1A1
ENSEMBL:ENSG00000108821 COL1A1
HGNC:2197 COL1A1
KEGG Gene (Homo sapiens):1277 COL1A1
Monarch:1277 COL1A1
NCBI Gene:1277 COL1A1
UCSC:P02452 COL1A1
Reference Transcript
RefSeq:NM_000088.3 COL1A1
Other Identifiers
11715350_a_at
11715351_at
11715352_x_at
11746872_a_at
1277
1556499_s_at
16846587
202310_s_at
202311_s_at
202312_s_at
217430_3p_x_at
217430_x_at
35473_at
35474_s_at
3762199
3762200
3762201
3762202
3762203
3762204
3762206
3762207
3762208
3762210
3762211
3762212
3762213
3762214
3762215
3762216
3762217
3762218
3762220
3762221
3762222
3762223
3762225
3762226
3762227
3762228
3762229
3762231
3762232
3762234
3762235
3762236
3762238
3762239
3762241
3762242
3762243
3762244
3762245
3762246
3762247
3762249
3762250
3762251
3762252
3762253
3762254
3762256
3762257
3762258
3762259
3762260
3762262
3762263
3762264
3762265
3762266
3762267
3762268
3762269
3762270
8016646
A_33_P3304668
GE60433
GE80888
GO:0001501
GO:0001503
GO:0001568
GO:0001649
GO:0001957
GO:0001958
GO:0002020
GO:0002376
GO:0003674
GO:0005198
GO:0005201
GO:0005515
GO:0005575
GO:0005576
GO:0005581
GO:0005584
GO:0005615
GO:0005622
GO:0005737
GO:0005783
GO:0005788
GO:0005794
GO:0006810
GO:0006950
GO:0007155
GO:0007165
GO:0007267
GO:0007584
GO:0007596
GO:0007601
GO:0007605
GO:0008150
GO:0009058
GO:0009612
GO:0009790
GO:0010718
GO:0010812
GO:0015031
GO:0019899
GO:0030020
GO:0030141
GO:0030154
GO:0030168
GO:0030198
GO:0030199
GO:0030335
GO:0031012
GO:0031410
GO:0031667
GO:0031960
GO:0032355
GO:0032964
GO:0032991
GO:0034504
GO:0034505
GO:0034641
GO:0038063
GO:0040011
GO:0042060
GO:0042493
GO:0042542
GO:0042802
GO:0043167
GO:0043226
GO:0043434
GO:0043588
GO:0043589
GO:0044344
GO:0044691
GO:0045893
GO:0046872
GO:0048407
GO:0048545
GO:0048646
GO:0048705
GO:0048706
GO:0048856
GO:0048870
GO:0050776
GO:0050877
GO:0050900
GO:0051591
GO:0055093
GO:0060325
GO:0060346
GO:0060351
GO:0062023
GO:0071230
GO:0071260
GO:0071300
GO:0071306
GO:0071356
GO:0071364
GO:0071560
GO:0090263
GO:1902617
GO:1902618
Hs.172928.0.A1_3p_a_at
Hs.172928.0.A2_3p_a_at
Hs2.433191.1.A1_3p_s_at
ILMN_1701308
M55998_s_at
PH_hs_0010359
TC17001682.hg
Z74615_at
g4502944_3p_a_at
Participant Of
hasMember
Alpha-1(I) -N propeptides [extracellular region]
Other forms of this molecule
3x4Hyp-3Hyp-GlcGalHyl-COL1A1(23-1464) [endoplasmic reticulum lumen]
3x4Hyp-GlcGalHyl-COL1A1(23-1464) [endoplasmic reticulum lumen]
GlcGalHyl-COL1A1(23-1464) [endoplasmic reticulum lumen]
GalHyl-COL1A1(23-1464) [endoplasmic reticulum lumen]
3x4Hyp-3Hyp-GalHyl-COL1A1(23-1464) [endoplasmic reticulum lumen]
3x4Hyp-GalHyl-COL1A1(23-1464) [endoplasmic reticulum lumen]
COL1A1(23-1464) [endoplasmic reticulum lumen]
3x4Hyp-COL1A1(23-1464) [endoplasmic reticulum lumen]
3x4Hyp-3Hyp-COL1A1(23-1464) [endoplasmic reticulum lumen]
3x4Hyp-5Hyl-COL1A1(23-1464) [endoplasmic reticulum lumen]
3x4Hyp-3Hyp-5Hyl-COL1A1(23-1464) [endoplasmic reticulum lumen]
5Hyl-COL1A1(23-1464) [endoplasmic reticulum lumen]
Lysyl-pyrrolyl 5-hydroxylysyl collagen alpha-1(I) chain [extracellular region]
Lysyl-pyrrolyl 3,4-Hyp 5-Hyl collagen alpha-1(I) chain [extracellular region]
Lysyl-pyrrolyl 4-Hyp 5-Hyl collagen alpha-1(I) chain [extracellular region]
Lysyl-pyridinolyl 5-hydroxylysyl collagen alpha-1(I) chain [extracellular region]
Lysyl-pyridinolyl 4-Hyp 5-Hyl collagen alpha-1(I) chain [extracellular region]
Lysyl-pyridinolyl 3,4-Hyp 5-Hyl collagen alpha-1(I) chain [extracellular region]
Dehydrolysinonorlysyl 4-hydroxyprolyl collagen alpha-1(I) chain [extracellular region]
Dehydrolysinonorlysyl 4-Hyp 5-Gal-Hyl collagen alpha-1(I) chain [extracellular region]
Dehydrolysinonorlysyl 3,4-hydroxyprolyl collagen alpha-1(I) chain [extracellular region]
Dehydrolysinonorlysyl 4-Hyp 5-Hyl collagen alpha-1(I) chain [extracellular region]
Dehydrolysinonorlysyl 4-Hyp Glu-Gal-Hyl collagen alpha-1(I) chain [extracellular region]
Dehydrolysinonorlysyl Collagen alpha-1(I) chain [extracellular region]
Dehydrolysinonorlysyl 5-Gal-Hyl collagen alpha-1(I) chain [extracellular region]
Dehydrolysinonorlysyl 3,4-Hyp 5-Gal-Hyl collagen alpha-1(I) chain [extracellular region]
Dehydrolysinonorlysyl Glu-Gal-Hyl collagen alpha-1(I) chain [extracellular region]
Dehydrolysinonorlysyl 3,4-Hyp 5-Hyl collagen alpha-1(I) chain [extracellular region]
Dehydrolysinonorlysyl 3,4-Hyp Glu-Gal-Hyl collagen alpha-1(I) chain [extracellular region]
Dehydrolysinonorlysyl 5-hydroxylysl-collagen alpha-1(I) chain [extracellular region]
Hydroxylysyl-pyrrolyl 4-Hyp 5-Hyl collagen alpha-1(I) chain [extracellular region]
Hydroxylysyl-pyrrolyl 3,4-Hyp 5-Hyl collagen alpha-1(I) chain [extracellular region]
Hydroxylysyl-pyrrolyl 5-hydroxylysyl collagen alpha-1(I) chain [extracellular region]
Lysino-5-ketonorlysyl 5-hydroxylysl-collagen alpha-1(I) chain [extracellular region]
Lysino-5-ketonorlysyl 4-Hyp 5-Hyl collagen alpha-1(I) chain [extracellular region]
Lysino-5-ketonorlysyl 3,4-Hyp 5-Hyl collagen alpha-1(I) chain [extracellular region]
3x4Hyp-3Hyp-Alys-COL1A1 [extracellular region]
Alys-COL1A1 [extracellular region]
3x4Hyp-Alys-COL1A1 [extracellular region]
Alys-GalHyl-COL1A1 [extracellular region]
3x4Hyp-Alys-GlcGalHyl-COL1A1 [extracellular region]
3x4Hyp-3Hyp-5Hyl-Alys-COL1A1 [extracellular region]
3x4Hyp-5Hyl-Alys-COL1A1 [extracellular region]
3x4Hyp-3Hyp-Alys-GlcGalHyl-COL1A1 [extracellular region]
Alys-GlcGalHyl-COL1A1 [extracellular region]
3x4Hyp-Alys-GalHyl-COL1A1 [extracellular region]
5Hyl-Alys-COL1A1 [extracellular region]
3x4Hyp-3Hyp-Alys-GalHyl-COL1A1 [extracellular region]
Dehydrohydroxylysinonorlysyl Glu-Gal-Hyl collagen alpha-1(I) chain [extracellular region]
Dehydrohydroxylysinonorlysyl 3,4-hydroxyprolyl collagen alpha-1(I) chain [extracellular region]
Dehydrohydroxylysinonorlysyl 3,4-Hyp Glu-Gal-Hyl collagen alpha-1(I) chain [extracellular region]
Dehydrohydroxylysinonorlysyl 5-Gal-Hyl collagen alpha-1(I) chain [extracellular region]
Dehydrohydroxylysinonorlysyl 3,4-Hyp 5-Gal-Hyl collagen alpha-1(I) chain [extracellular region]
Dehydrohydroxylysinonorlysyl 4-Hyp Glu-Gal-Hyl collagen alpha-1(I) chain [extracellular region]
Dehydrohydroxylysinonorlysyl 5-hydroxylysl-collagen alpha-1(I) chain [extracellular region]
Dehydrohydroxylysinonorlysyl Collagen alpha-1(I) chain [extracellular region]
Dehydrohydroxylysinonorlysyl 4-hydroxyprolyl collagen alpha-1(I) chain [extracellular region]
Dehydrohydroxylysinonorlysyl 4-Hyp 5-Hyl collagen alpha-1(I) chain [extracellular region]
Dehydrohydroxylysinonorlysyl 3,4-Hyp 5-Hyl collagen alpha-1(I) chain [extracellular region]
Dehydrohydroxylysinonorlysyl 4-Hyp 5-Gal-Hyl collagen alpha-1(I) chain [extracellular region]
Hydroxylysyl-pyridinolyl 5-hydroxylysyl collagen alpha-1(I) chain [extracellular region]
Hydroxylysyl-pyridinolyl 3,4-Hyp 5-Hyl collagen alpha-1(I) chain [extracellular region]
Hydroxylysyl-pyridinolyl 4-Hyp 5-Hyl collagen alpha-1(I) chain [extracellular region]
Hydroxylysino-5-ketonorlysyl 4-Hyp 5-Hyl collagen alpha-1(I) chain [extracellular region]
Hydroxylysino-5-ketonorlysyl 3,4-Hyp 5-Hyl collagen alpha-1(I) chain [extracellular region]
Hydroxylysino-5-ketonorlysyl 5-hydroxylysyl-collagen alpha-1(I) chain [extracellular region]
Hydroxyallysyl 5-hydroxylysyl collagen alpha-1(I) chain [extracellular region]
Hydroxyallysyl 3,4-Hyp 5-Hyl collagen alpha-1(I) chain [extracellular region]
Hydroxyallysyl 4-Hyp 5-Hyl collagen alpha-1(I) chain [extracellular region]
3x4Hyp-3Hyp-GalHyl-COL1A1(23-1464) [extracellular region]
GalHyl-COL1A1(23-1464) [extracellular region]
3x4Hyp-3Hyp-GlcGalHyl-COL1A1(23-1464) [extracellular region]
GlcGalHyl-COL1A1(23-1464) [extracellular region]
3x4Hyp-GalHyl-COL1A1(23-1464) [extracellular region]
3x4Hyp-3Hyp-5Hyl-COL1A1(23-1464) [extracellular region]
COL1A1(23-1464) [extracellular region]
3x4Hyp-3Hyp-COL1A1(23-1464) [extracellular region]
3x4Hyp-GlcGalHyl-COL1A1(23-1464) [extracellular region]
5Hyl-COL1A1(23-1464) [extracellular region]
3x4Hyp-5Hyl-COL1A1(23-1464) [extracellular region]
3x4Hyp-COL1A1(23-1464) [extracellular region]
3x4Hyp-GlcGalHyl-COL1A1(162-1464) [extracellular region]
3x4Hyp-GalHyl-COL1A1(162-1464) [extracellular region]
3x4Hyp-3Hyp-GalHyl-COL1A1(162-1464) [extracellular region]
3x4Hyp-5Hyl-COL1A1(162-1464) [extracellular region]
5Hyl-COL1A1(162-1464) [extracellular region]
GlcGalHyl-COL1A1(162-1464) [extracellular region]
3x4Hyp-3Hyp-GlcGalHyl-COL1A1(162-1464) [extracellular region]
3x4Hyp-3Hyp-5Hyl-COL1A1(162-1464) [extracellular region]
GalHyl-COL1A1(162-1464) [extracellular region]
3x4Hyp-COL1A1(162-1464) [extracellular region]
3x4Hyp-3Hyp-COL1A1(162-1464) [extracellular region]
3x4Hyp-3Hyp-COL1A1(954-1218) [extracellular region]
3x4Hyp-3Hyp-GlcGalHyl-COL1A1(954-1218) [extracellular region]
GlcGalHyl-COL1A1(162-953) [extracellular region]
COL1A1(954-1218) [extracellular region]
3x4Hyp-GalHyl-COL1A1(162-953) [extracellular region]
3x4Hyp-GalHyl-COL1A1(954-1218) [extracellular region]
3x4Hyp-3Hyp-GlcGalHyl-COL1A1(162-953) [extracellular region]
3x4Hyp-5Hyl-COL1A1(954-1218) [extracellular region]
3x4Hyp-3Hyp-GalHyl-COL1A1(954-1218) [extracellular region]
3x4Hyp-GlcGalHyl-COL1A1(162-953) [extracellular region]
3x4Hyp-5Hyl-COL1A1(162-953) [extracellular region]
3x4Hyp-3Hyp-5Hyl-COL1A1(954-1218) [extracellular region]
3x4Hyp-3Hyp-GalHyl-COL1A1(162-953) [extracellular region]
GalHyl-COL1A1(954-1218) [extracellular region]
3x4Hyp-3Hyp-5Hyl-COL1A1(162-953) [extracellular region]
5Hyl-COL1A1(954-1218) [extracellular region]
3x4Hyp-COL1A1(162-953) [extracellular region]
3x4Hyp-GlcGalHyl-COL1A1(954-1218) [extracellular region]
GalHyl-COL1A1(162-953) [extracellular region]
GlcGalHyl-COL1A1(954-1218) [extracellular region]
COL1A1(162-953) [extracellular region]
3x4Hyp-COL1A1(954-1218) [extracellular region]
3x4Hyp-3Hyp-COL1A1(162-953) [extracellular region]
5Hyl-COL1A1(162-953) [extracellular region]
3x4Hyp-GlcGalHyl-COL1A1 [extracellular region]
GlcGalHyl-COL1A1 [extracellular region]
GalHyl-COL1A1 [extracellular region]
3x4Hyp-3Hyp-GalHyl-COL1A1 [extracellular region]
3x4Hyp-3Hyp-GlcGalHyl-COL1A1 [extracellular region]
COL1A1 [extracellular region]
3x4Hyp-5Hyl-COL1A1 [extracellular region]
5Hyl-COL1A1 [extracellular region]
3x4Hyp-3Hyp-COL1A1 [extracellular region]
3x4Hyp-COL1A1 [extracellular region]
3x4Hyp-3Hyp-5Hyl-COL1A1 [extracellular region]
3x4Hyp-GalHyl-COL1A1 [extracellular region]
Inferred To
Col1a1 [extracellular region] (Mus musculus)
Col1a1 [extracellular region] (Rattus norvegicus)
COL1A1(162-1464) [extracellular region] (Dictyostelium discoideum)
COL1A1(162-1464) [extracellular region] (Sus scrofa)
tbc1d31 [extracellular region] (Xenopus tropicalis)
col1a1a [extracellular region] (Danio rerio)
Cross References
RefSeq
NP_000079.2
OpenTargets
ENSG00000108821
HPA
ENSG00000108821-COL1A1
GeneCards
P02452
Ensembl
ENST00000225964
,
ENSG00000108821
,
ENSP00000225964
PRO
P02452
Orphanet
15767
HMDB Protein
HMDBP01757
PDB
5CTD
,
5OU9
,
2LLP
,
1Q7D
,
5K31
,
3GXE
,
5CVB
,
5OU8
,
3EJH
,
5CTI
,
5CVA
Interactors (3)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P02751 FN1
8
FN1(32-271) [extracellular region]
(R-HSA-3787935)
FN1(32-2386) [platelet alpha granule lumen]
(R-HSA-114620)
FN1(272-2386) [extracellular region]
(R-HSA-3788024)
FN1(32-?) [extracellular region]
(R-HSA-2533850)
FN1(?-2386) [extracellular region]
(R-HSA-2533841)
p-FN1 [endoplasmic reticulum lumen]
(R-HSA-8956937)
FN1 [endoplasmic reticulum lumen]
(R-HSA-8956708)
FN1(32-2386) [extracellular region]
(R-HSA-54851)
0.623
2
UniProt:O01949 ALL3
0.598
5
UniProt:Q14145 KEAP1
2
KEAP1 [cytosol]
(R-HSA-976038)
Ub-KEAP1 [cytosol]
(R-HSA-6782766)
0.556
3
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