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Collagen XI cross-links with collagen II
Stable Identifier
R-HSA-2299620
Type
Reaction [binding]
Species
Homo sapiens
Compartment
extracellular region
ReviewStatus
5/5
Locations in the PathwayBrowser
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Extracellular matrix organization (Homo sapiens)
Collagen formation (Homo sapiens)
Assembly of collagen fibrils and other multimeric structures (Homo sapiens)
Collagen XI cross-links with collagen II (Homo sapiens)
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The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
Type XI collagen molecules are cross-linked by lysyl oxidase-mediated bonds (Wu & Eyre 1995) primarily in a head-to-tail manner (Eyre et al. 2006). Homopolymers of type XI collagen can form in vitro (Bruckner & van der Rest 1994, Blaschke et al. 2000). Type XI collagen molecules can cross-link with type II collagen forming heterofibrils (Eyre & Wu 2004, 2005).
Literature References
PubMed ID
Title
Journal
Year
14602708
Covalent cross-linking of the NC1 domain of collagen type IX to collagen type II in cartilage
Weis, MA
,
Pietka, T
,
Eyre, DR
,
Wu, JJ
J Biol Chem
2004
Participants
Input
Collagen type II fibril [extracellular region]
(Homo sapiens)
Collagen type XI fibril [extracellular region]
(Homo sapiens)
Output
Collagen type XI fibril:Collagen type II fibril [extracellular region]
(Homo sapiens)
Participates
as an event of
Assembly of collagen fibrils and other multimeric structures (Homo sapiens)
Orthologous Events
Collagen XI cross-links with collagen II (Bos taurus)
Collagen XI cross-links with collagen II (Canis familiaris)
Collagen XI cross-links with collagen II (Mus musculus)
Collagen XI cross-links with collagen II (Rattus norvegicus)
Collagen XI cross-links with collagen II (Sus scrofa)
Authored
Jupe, S (2012-04-30)
Reviewed
Raleigh, S (2012-10-08)
Ricard-Blum, S (2012-11-19)
Kalamajski, S (2012-10-08)
Created
Jupe, S (2012-05-31)
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