Formation of hydroxylysino-5-ketonorleucine cross-links

Stable Identifier
R-HSA-2395302
Type
Reaction
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

Hydroxyallysine and hydroxylysine can react forming the Schiff base, which spontaneously undergoes an Amadori rearrangement resulting in the ketoimine cross-link hydroxylysino-5-ketonorleucine (HLKNL). This is much more stable than the aldimine crosslinks (Bailey et al. 1998).

Literature References
Participants
Participant Of
Orthologous Events