Formation of lysyl-pyridinoline cross-links

Stable Identifier
R-HSA-2395322
Type
Reaction
Species
Homo sapiens
Compartment
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Summation

Lysyl-pyridinoline (L-Pyr) cross-links are formed from two hydroxylysine residues and a lysine residue (LKNL plus a further hydroxyallysine contributed by HLKNL), found mostly in calcified tissues (Bailey et al. 1998).

Literature References
PubMed ID Title Journal Year
6129847 Collagen cross-linking: lysyl oxidase dependent synthesis of pyridinoline in vitro: confirmation that pyridinoline is derived from collagen

Siegel, RC, Fu, JC, Uto, N, Horiuchi, K, Fujimoto, D

Biochem. Biophys. Res. Commun. 1982
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