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MFAP1 [nucleoplasm]
Stable Identifier
R-HSA-2396419
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
Microfibrillar-associated protein 1, MFAP1_HUMAN
Locations in the PathwayBrowser
Expand all
Metabolism of RNA (Homo sapiens)
Processing of Capped Intron-Containing Pre-mRNA (Homo sapiens)
mRNA Splicing (Homo sapiens)
mRNA Splicing - Major Pathway (Homo sapiens)
Formation of the Spliceosomal B complex (Homo sapiens)
MFAP1 [nucleoplasm] (Homo sapiens)
Spliceosomal B complex [nucleoplasm] (Homo sapiens)
MFAP1 [nucleoplasm] (Homo sapiens)
Formation of the Spliceosomal B* complex (Homo sapiens)
MFAP1 [nucleoplasm] (Homo sapiens)
Spliceosomal Bact complex [nucleoplasm] (Homo sapiens)
MFAP1 [nucleoplasm] (Homo sapiens)
Formation of the Spliceosomal Bact complex (Homo sapiens)
Spliceosomal B complex [nucleoplasm] (Homo sapiens)
MFAP1 [nucleoplasm] (Homo sapiens)
Spliceosomal Bact complex [nucleoplasm] (Homo sapiens)
MFAP1 [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:P55081 MFAP1
Gene Names
MFAP1
Chain
initiator methionine:, chain:2-439
Reference Genes
BioGPS Gene:4236 MFAP1
COSMIC (genes):MFAP1 MFAP1
CTD Gene:4236 MFAP1
dbSNP Gene:4236 MFAP1
ENSEMBL:ENSG00000140259 MFAP1
HGNC:7032 MFAP1
KEGG:hsa:4236 MFAP1
Monarch:4236 MFAP1
NCBI Gene:4236 MFAP1
OMIM:600215 MFAP1
UCSC:P55081 MFAP1
Reference Transcript
RefSeq:NM_005926.2 MFAP1
Other Identifiers
11721251_at
16808386
203406_PM_at
203406_at
3621693
3621694
3621695
3621696
3621697
3621698
3621699
3621701
3621706
3621708
3621709
3621710
3621711
3621712
3621713
3621716
3621718
3621719
3621720
3621721
36535_at
4236
7988245
A_23_P14636
GE58872
GO:0000398
GO:0001527
GO:0003723
GO:0005515
GO:0005634
GO:0005654
GO:0005681
GO:0005684
GO:0005813
GO:0005815
GO:0006397
GO:0008380
GO:0016071
GO:0043226
GO:0071005
HMNXSV003037803
ILMN_1676799
PH_hs_0003900
PH_hs_0031276
TC15001287.hg
U04209_at
g5174552_3p_at
Participates
as an input of
Formation of the Spliceosomal B complex (Homo sapiens)
as a component of
Spliceosomal B complex [nucleoplasm] (Homo sapiens)
Spliceosomal Bact complex [nucleoplasm] (Homo sapiens)
as an output of
Formation of the Spliceosomal B* complex (Homo sapiens)
Inferred To
Mfap1al1 [nucleoplasm]
(Rattus norvegicus)
MFAP1 [nucleoplasm]
(Bos taurus)
MFAP1 [nucleoplasm]
(Canis familiaris)
MFAP1 [nucleoplasm]
(Gallus gallus)
MFAP1 [nucleoplasm]
(Plasmodium falciparum)
MFAP1 [nucleoplasm]
(Schizosaccharomyces pombe)
MFAP1 [nucleoplasm]
(Sus scrofa)
mfap-1 [nucleoplasm]
(Caenorhabditis elegans)
mfap1 [nucleoplasm]
(Danio rerio)
mfap1 [nucleoplasm]
(Dictyostelium discoideum)
mfap1 [nucleoplasm]
(Xenopus tropicalis)
Mfap1b [nucleoplasm]
(Mus musculus)
Mfap1a [nucleoplasm]
(Mus musculus)
Homologues of MFAP1 [nucleoplasm]
(Mus musculus)
Mfap1 [nucleoplasm]
(Drosophila melanogaster)
Cross References
RefSeq
NP_005917.2
OpenTargets
ENSG00000140259
ENSEMBL
ENST00000267812
,
ENSP00000267812
HPA
ENSG00000140259-MFAP1
PRO
P55081
Pharos - Targets
P55081
GlyGen
P55081
PDB
8QO9
,
7ABI
,
8QPE
,
7ABF
,
8H6K
,
7ABG
,
7AAV
,
6AHD
,
5F5S
,
5O9Z
,
8Q7N
,
8QZS
Interactors (99)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q8TD17 ZNF398
1
ZNF398 [nucleoplasm]
(R-HSA-1247512)
0.781
7
UniProt:Q9H079 KTBL1
0.781
7
UniProt:Q08379 GOLGA2
3
p-S37-GOLGA2 [Golgi membrane]
(R-HSA-2172179)
GOLGA2 [endoplasmic reticulum-Golgi intermediate compartment membrane]
(R-HSA-2167933)
GOLGA2 [Golgi membrane]
(R-HSA-6808764)
0.718
6
UniProt:Q9Y6D9 MAD1L1
1
MAD1L1 [cytosol]
(R-HSA-141433)
0.718
6
UniProt:Q9BYV2 TRI54
0.718
6
UniProt:O95751 LDOC1
0.718
6
UniProt:Q8N7W2-2 BEND7
0.718
6
UniProt:Q9UJV3-2 MID2
0.718
6
UniProt:Q53EZ4 CEP55
0.718
6
UniProt:P51116 FXR2
0.718
6
UniProt:Q8N1B4 VPS52
1
VPS52 [trans-Golgi network membrane]
(R-HSA-6811029)
0.718
6
UniProt:Q8NHQ1 CEP70
1
CEP70 [cytosol]
(R-HSA-380257)
0.718
6
UniProt:Q6NT76 HMBX1
0.718
6
UniProt:Q8NAV1 PRPF38A
1
PRPF38A [nucleoplasm]
(R-HSA-8867897)
0.671
4
UniProt:Q8TAD8 SNIP1
1
SNIP1 [nucleoplasm]
(R-HSA-3222315)
0.666
4
UniProt:P61981 YWHAG
1
YWHAG [cytosol]
(R-HSA-380312)
0.589
2
UniProt:Q96MF2 STAC3
0.556
3
UniProt:P38432 COIL
0.556
3
UniProt:P19237 TNNI1
1
TNNI1 [cytosol]
(R-HSA-390539)
0.556
3
UniProt:Q9NWS0 PIHD1
0.556
3
UniProt:P51114-2 FXR1
0.556
3
UniProt:O94868-3 FCHSD2
0.556
3
UniProt:Q8IZU0 FAM9B
0.556
3
UniProt:Q68D86 C102B
0.556
3
UniProt:Q9Y2J4 AMOTL2
1
AMOTL2 [cytosol]
(R-HSA-2028606)
0.556
3
UniProt:Q96BR9 ZBT8A
0.556
3
UniProt:Q08117-2 TLE5
0.556
5
UniProt:Q6ZNG0 ZNF620
1
ZNF620 [nucleoplasm]
(R-HSA-2127603)
0.556
3
UniProt:P52741 ZN134
0.556
3
UniProt:Q9NSC5 HOMER3
1
HOMER3 [cytosol]
(R-HSA-6794236)
0.556
3
UniProt:O75031 HSF2B
0.556
3
UniProt:O75558 STX11
0.556
3
UniProt:Q8TAP6 CEP76
1
CEP76 [cytosol]
(R-HSA-380281)
0.556
3
UniProt:Q8IYX8 CE57L
0.556
3
UniProt:Q9Y2J4-4 AMOTL2
0.556
3
UniProt:Q9H8W4 PKHF2
0.556
3
UniProt:Q5JR59 MTUS2
0.556
3
UniProt:A6NEM1 GG6L9
0.556
3
UniProt:Q2TAC2 CCD57
0.556
3
UniProt:Q8NEJ9 NGDN
0.556
3
UniProt:Q8N8Y5 ZFP41
0.556
3
UniProt:Q96NG5 ZNF558
1
ZNF558 [nucleoplasm]
(R-HSA-1973893)
0.556
3
UniProt:Q9Y250 LZTS1
0.556
3
UniProt:Q96GN5 CDA7L
0.556
3
UniProt:Q6PI77 GASP3
0.556
3
UniProt:Q9H2G9 BLZF1
1
BLZF1 [Golgi membrane]
(R-HSA-2422372)
0.556
3
UniProt:Q8IWZ5 TRI42
0.556
3
UniProt:O14777 NDC80
1
NDC80 [cytosol]
(R-HSA-375314)
0.556
3
UniProt:Q9H257-2 CARD9
0.556
3
UniProt:Q4G0R1 Q4G0R1
0.556
3
UniProt:Q9UDV6 ZNF212
1
ZNF212 [nucleoplasm]
(R-HSA-1027348)
0.556
3
UniProt:Q96IK5 GMCL1
0.556
3
UniProt:P36508 ZNF76
0.556
3
UniProt:Q9NVV9 THAP1
0.556
3
UniProt:O43829 ZBT14
0.556
3
IntAct:EBI-16439879 CCSB ORF ID
0.556
3
UniProt:Q96ED9-2 HOOK2
0.556
3
UniProt:Q9Y2V7 COG6
2
COG6 [trans-Golgi network membrane]
(R-HSA-6813872)
COG6 [Golgi membrane]
(R-HSA-2980958)
0.556
3
UniProt:Q4V328 GRAP1
0.556
3
UniProt:Q96BT7-2 ALKBH8
0.556
3
UniProt:Q96JM7-2 L3MBTL3
0.556
3
UniProt:Q9NTW7 ZF64B
0.556
3
UniProt:O75478 TADA2A
1
TADA2A [nucleoplasm]
(R-HSA-3662284)
0.556
3
UniProt:Q8TDR4 TCP1L
0.556
3
UniProt:Q8IYX8-2 CEP57L1
0.556
3
UniProt:Q8TD10 MIPO1
0.556
3
UniProt:Q9Y2K1 ZBTB1
0.556
3
UniProt:Q12933 TRAF2
5
TRAF2 [cytosol]
(R-HSA-66370)
PolyUb-TRAF2 [cytosol]
(R-HSA-6782848)
K63polyUb-TRAF2 [cytosol]
(R-HSA-8862193)
K63polyUb-TRAF2 [nucleoplasm]
(R-HSA-8862194)
TRAF2 [nucleoplasm]
(R-HSA-8862199)
0.556
3
UniProt:Q9H257 CARD9
3
CARD9 [cytosol]
(R-HSA-561194)
p-T231-CARD9 [plasma membrane]
(R-HSA-5607623)
CARD9 [plasma membrane]
(R-HSA-5607662)
0.556
3
UniProt:Q96CW1 AP2M1
6
AP2M1 [plasma membrane]
(R-HSA-167585)
AP2M1 [lysosomal membrane]
(R-HSA-196144)
AP2M1 [cytosol]
(R-HSA-182227)
AP2M1 [clathrin-coated endocytic vesicle membrane]
(R-HSA-2130423)
AP2M1 [endolysosome membrane]
(R-HSA-6784828)
p-T156 AP2M1 [cytosol]
(R-HSA-8856805)
0.556
3
UniProt:Q9UBB9 TFIP11
1
TFIP11 [nucleoplasm]
(R-HSA-8869310)
0.556
3
UniProt:P26367 PAX6
1
PAX6 [nucleoplasm]
(R-HSA-3009044)
0.556
3
UniProt:Q08117 TLE5
1
AES [nucleoplasm]
(R-HSA-4648963)
0.556
3
UniProt:O95995 GAS8
1
GAS8 [cytosol]
(R-HSA-5633057)
0.556
3
UniProt:Q9UGI0 ZRANB1
1
ZRANB1 [cytosol]
(R-HSA-6781939)
0.556
3
UniProt:Q8IXK0 PHC2
1
PHC2 [nucleoplasm]
(R-HSA-389112)
0.556
3
UniProt:Q6P2D0 ZFP1
1
ZFP1 [nucleoplasm]
(R-HSA-974997)
0.556
3
UniProt:Q96EZ8 MCRS1
1
MCRS1 [nucleoplasm]
(R-HSA-3321849)
0.556
3
UniProt:Q9BVG8-5 KIFC3
0.556
3
UniProt:Q7RTU3 OLIG3
0.556
3
UniProt:Q9NQZ8 ZNF71
1
ZNF71 [nucleoplasm]
(R-HSA-2454145)
0.556
3
UniProt:Q6A162 KRT40
1
KRT40 [cytosol]
(R-HSA-6809605)
0.556
3
UniProt:Q03252 LMNB2
0.556
3
UniProt:Q8TD16-2 BICD2
0.556
3
UniProt:Q96N21 AP4AT
0.556
3
UniProt:O60729 CDC14B
1
CDC14B [nucleoplasm]
(R-HSA-3214897)
0.556
3
UniProt:Q96BK5 PINX1
0.556
3
UniProt:Q5W5X9-3 TTC23
0.556
3
UniProt:O95198 KLHL2
1
KLHL2 [cytosol]
(R-HSA-8863217)
0.556
3
UniProt:Q8WV44 TRIM41
1
TRIM41 [cytosol]
(R-HSA-5688975)
0.556
3
UniProt:Q9Y2D8 ADIP
0.556
3
UniProt:P51814-6 ZNF41
0.556
3
UniProt:Q9H147 TDIF1
0.556
3
UniProt:Q9BVG8 KIFC3
0.556
3
UniProt:Q15695 U2AFL
0.556
3
UniProt:Q5VSY0 GKAP1
0.556
3
UniProt:Q13123 IK
1
IK [nucleoplasm]
(R-HSA-9770239)
0.508
2
UniProt:O43395 PRPF3
1
PRPF3 [nucleoplasm]
(R-HSA-6806806)
0.508
2
UniProt:Q14978 NOLC1
0.48
2
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