AKT1 E17K mutant phosphorylates CREB1

Stable Identifier
R-HSA-2399996
Type
Reaction
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

AKT1 E17K gain-of-function mutant is expected to phosphorylate CREB1, like the wild-type AKT (Du et al. 1998), but this has not been experimentally tested.

Literature References
PubMed ID Title Journal Year
9829964 CREB is a regulatory target for the protein kinase Akt/PKB J Biol Chem 1998
Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
protein serine/threonine kinase activity of p-T308,S473-AKT1 E17K [nucleoplasm]
Physical Entity
Activity
Disease
Name Identifier Synonyms
cancer 162 malignant tumor, malignant neoplasm, primary cancer