AKT1 E17K gain-of-function mutant is expected to translocate to the nucleus, like the wild-type AKT (Borgatti et al. 2003), but this has not been directly experimentally tested.
Neri, LM, Capitani, S, Bellacosa, A, Tabellini, G, Martelli, AM, Borgatti, P
Gain of function of p-T308,S473-AKT1 E17K [cytosol]
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