GSSeH condenses with GSH to form H2Se and GSSG

Stable Identifier
R-HSA-2408500
Type
Reaction [transition]
Species
Homo sapiens
Compartment
cytosol
ReviewStatus
5/5
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GSSeH condenses with GSH to form H2Se and GSSG
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Gluthathioselenol (GSSeH) and reduced glutathione (GSH) condense to form hydrogen selenide (H2Se) and glutathione disulfide (GSSG). This reaction is inferred from the event in rat (Bjornstedt et al. 1992).
Literature References
PubMed ID Title Journal Year
1569062 Selenodiglutathione is a highly efficient oxidant of reduced thioredoxin and a substrate for mammalian thioredoxin reductase

Björnstedt, M, Holmgren, A, Kumar, S

J. Biol. Chem. 1992
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GSSeH condenses with GSH to form H2Se and GSSG (Rattus norvegicus)
Authored
Williams, MG  (2014-05-06)
Reviewed
Rush, MG  (2015-08-30)
Created
Williams, MG  (2012-07-17)
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