Reactome | Sec-tRNA(Sec):EEFSEC:GTP binds to 80S Ribosome

Sec-tRNA(Sec):EEFSEC:GTP binds to 80S Ribosome

Stable Identifier

R-HSA-2408529

Type

Reaction [binding]

Species

Homo sapiens

Compartment

cytosol

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General

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SVG | | PPTX | SBGN

Sec-tRNA(Sec):EEFSEC:GTP binds to 80S Ribosome

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The complex consisting of selenocysteinyl (Sec) transfer RNA (tRNA) for Sec (Sec-tRNASec), selenocysteine-specific elongation factor (EEFSEC) aka SelB, selenocysteine insertion sequence-binding protein 2 (SECISBP2) aka SBP2 and GTP interacts with the 80S ribosomal protein complex (80S:Met-tRNAi:mRNA). This reaction is inferred from events occurring in rats.

Literature References

PubMed ID	Title	Journal	Year
15821744	Ribosomal protein L30 is a component of the UGA-selenocysteine recoding machinery in eukaryotes Chavatte, L, Brown, BA, Driscoll, DM	Nat. Struct. Mol. Biol.	2005