AdeSeHCys is hydrolysed to SeHCys by AHCY

Stable Identifier
R-HSA-2408532
Type
Reaction [transition]
Species
Homo sapiens
Compartment
cytosol
ReviewStatus
5/5
Locations in the PathwayBrowser
Expand all
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
AdeSeHCys is hydrolysed to SeHCys by AHCY
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
Adenosylhomocysteinase (AHCY) is involved in the hydrolysis of adenosylselenohomocysteine (AdeSeHCys) into adenosine and selenohomocysteine (SeHCys). This reaction is inferred from the event in rat involving the protein adenosylhomocysteinase (Ahcy) (Kajander et al. 1991, Kajander and Raina 1981).
Literature References
PubMed ID Title Journal Year
1711890 Metabolism, cellular actions, and cytotoxicity of selenomethionine in cultured cells

Akerman, KK, Kärenlampi, SO, Martikainen, H, Harvima, RJ, Kajander, EO, Kantola, M, Eloranta, TO

Biol Trace Elem Res 1991
7305945 Affinity-chromatographic purification of S-adenosyl-L-homocysteine hydrolase. Some properties of the enzyme from rat liver

Raina, AM, Kajander, EO

Biochem. J. 1981
Participants
Input
Output
Participates
as an event of
Catalyst Activity

adenosylselenohomocysteinase activity of AHCY [cytosol]

Physical Entity
AHCY [cytosol] (Homo sapiens)
Activity
adenosylselenohomocysteinase activity (GO:0098604)
Inferred From
AdeSeHCys is hydrolysed to SeHCys by Ahcy (Rattus norvegicus)
Authored
Williams, MG  (2014-05-06)
Reviewed
Rush, MG  (2015-08-30)
Created
Williams, MG  (2012-07-17)
Cite Us!