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p-T222,T225-GORASP2 [Golgi membrane]
Stable Identifier
R-HSA-2422965
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
Golgi membrane
Locations in the PathwayBrowser
Expand all
Cell Cycle (Homo sapiens)
Cell Cycle, Mitotic (Homo sapiens)
M Phase (Homo sapiens)
Mitotic Prophase (Homo sapiens)
Golgi Cisternae Pericentriolar Stack Reorganization (Homo sapiens)
GORASP1 phosphorylated by PLK1 and GORASP2 phosphorylated by MAPK3-3/MAPK1 are unable to promote Golgi cisternae stacking (Homo sapiens)
p-T222,225-GORASP2:BLZF1:RAB2A:GTP [Golgi membrane] (Homo sapiens)
p-T222,T225-GORASP2 [Golgi membrane] (Homo sapiens)
MAPK3-3 or MAPK1 phosphorylate GORASP2 (Homo sapiens)
p-T222,225-GORASP2:BLZF1:RAB2A:GTP [Golgi membrane] (Homo sapiens)
p-T222,T225-GORASP2 [Golgi membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9H8Y8 GORASP2
Gene Names
GORASP2, GOLPH6
Chain
initiator methionine:, chain:2-452
Reference Genes
BioGPS Gene:26003 GORASP2
COSMIC (genes):GORASP2 GORASP2
CTD Gene:26003 GORASP2
dbSNP Gene:26003 GORASP2
ENSEMBL:ENSG00000115806 GORASP2
HGNC:17500 GORASP2
KEGG:hsa:26003 GORASP2
Monarch:26003 GORASP2
NCBI Gene:26003 GORASP2
OMIM:608693 GORASP2
UCSC:Q9H8Y8 GORASP2
Reference Transcript
RefSeq:XM_006712408.2 GORASP2
RefSeq:NM_001201428.1 GORASP2
RefSeq:NM_015530.4 GORASP2
Other Identifiers
11742760_a_at
11742761_x_at
11747151_a_at
11751303_s_at
16887531
207812_PM_s_at
207812_s_at
208842_PM_s_at
208842_s_at
208843_PM_s_at
208843_s_at
2515058
2515060
2515061
2515062
2515063
2515064
2515069
2515070
2515071
2515072
2515073
2515074
2515075
2515076
2515077
2515080
2515081
2515085
2515087
2515094
2515095
2515096
2515097
2515098
26003
35805_at
8046306
A_14_P106528
A_14_P109579
A_23_P165494
A_24_P328320
GE56466
GO:0000139
GO:0005515
GO:0005783
GO:0005789
GO:0005794
GO:0005801
GO:0006996
GO:0007030
GO:0007283
GO:0016020
GO:0022414
GO:0030154
GO:0034976
GO:0043226
GO:0061951
GO:0070925
GO:0072659
HMNXSV003057684
Hs.6880.1.S1_3p_a_at
ILMN_1748018
PH_hs_0000700
RNA147143|p0247_imsncRNA388
g7661569_3p_a_at
Participates
as a component of
p-T222,225-GORASP2:BLZF1:RAB2A:GTP [Golgi membrane] (Homo sapiens)
Other forms of this molecule
GORASP2 [Golgi membrane]
Inferred To
phospho-GORASP2 [Golgi membrane]
(Bos taurus)
phospho-GORASP2 [Golgi membrane]
(Canis familiaris)
phospho-GORASP2 [Golgi membrane]
(Sus scrofa)
phospho-Gorasp2 [Golgi membrane]
(Mus musculus)
phospho-Gorasp2 [Golgi membrane]
(Rattus norvegicus)
phospho-gorasp2 [Golgi membrane]
(Danio rerio)
phospho-gorasp2 [Golgi membrane]
(Xenopus tropicalis)
phospho-Grasp65 [Golgi membrane]
(Drosophila melanogaster)
phospho-p-T222,T225-GORASP2 [Golgi membrane]
(Caenorhabditis elegans)
phospho-p-T222,T225-GORASP2 [Golgi membrane]
(Gallus gallus)
Modified Residues
Name
O-phospho-L-threonine at 225
Coordinate
225
PsiMod Name
O-phospho-L-threonine [MOD:00047]
PsiMod Definition
A protein modification that effectively converts an L-threonine residue to O-phospho-L-threonine.
Name
O-phospho-L-threonine at 222
Coordinate
222
PsiMod Name
O-phospho-L-threonine [MOD:00047]
PsiMod Definition
A protein modification that effectively converts an L-threonine residue to O-phospho-L-threonine.
Cross References
RefSeq
NP_056345.3
,
NP_001188357.1
,
XP_006712471.1
OpenTargets
ENSG00000115806
ENSEMBL
ENST00000234160
,
ENSP00000234160
HPA
ENSG00000115806-GORASP2
PRO
Q9H8Y8
Pharos - Targets
Q9H8Y8
GlyGen
Q9H8Y8
PDB
3RLE
,
4EDJ
Interactors (30)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q08379 GOLGA2
3
p-S37-GOLGA2 [Golgi membrane]
(R-HSA-2172179)
GOLGA2 [endoplasmic reticulum-Golgi intermediate compartment membrane]
(R-HSA-2167933)
GOLGA2 [Golgi membrane]
(R-HSA-6808764)
0.883
11
UniProt:Q12933 TRAF2
5
TRAF2 [cytosol]
(R-HSA-66370)
PolyUb-TRAF2 [cytosol]
(R-HSA-6782848)
K63polyUb-TRAF2 [cytosol]
(R-HSA-8862193)
K63polyUb-TRAF2 [nucleoplasm]
(R-HSA-8862194)
TRAF2 [nucleoplasm]
(R-HSA-8862199)
0.83
8
UniProt:P49247 RPIA
2
RPIA [cytosol]
(R-HSA-71304)
RPIA A61V [cytosol]
(R-HSA-5660009)
0.83
8
UniProt:P11926 ODC1
1
PXLP-K69-ODC1 [cytosol]
(R-HSA-70689)
0.781
11
UniProt:P40222 TXLNA
1
TXLNA [cytosol]
(R-HSA-449124)
0.781
7
UniProt:Q13077 TRAF1
3
TRAF1 [cytosol]
(R-HSA-5634163)
TRAF1(1-163) [cytosol]
(R-HSA-5634199)
TRAF1(164-416) [cytosol]
(R-HSA-5634204)
0.781
7
UniProt:Q14565 DMC1
1
DMC1 [nucleoplasm]
(R-HSA-912490)
0.781
8
UniProt:Q9GZQ8 MAP1LC3B
3
MAP1LC3B [cytosol]
(R-HSA-5205651)
MAP1LC3B(2-121) [cytosol]
(R-HSA-5682674)
MAP1LC3B [autophagosome membrane]
(R-HSA-5683641)
0.718
6
UniProt:Q08117 TLE5
1
AES [nucleoplasm]
(R-HSA-4648963)
0.666
4
UniProt:P13569 CFTR
17
misfolded CFTR [endoplasmic reticulum membrane]
(R-HSA-8868730)
CFTR [endoplasmic reticulum membrane]
(R-HSA-8866837)
CFTR [plasma membrane]
(R-HSA-383188)
CFTR N1303K [plasma membrane]
(R-HSA-5678983)
CFTR F508del [plasma membrane]
(R-HSA-5678978)
CFTR W1282* [plasma membrane]
(R-HSA-5678976)
CFTR G551D [plasma membrane]
(R-HSA-5678977)
CFTR G542* [plasma membrane]
(R-HSA-5678986)
ub-CFTR F508del [endoplasmic reticulum membrane]
(R-HSA-8866842)
ub-CFTR F508del [cytosol]
(R-HSA-8866838)
CFTR F508del [endoplasmic reticulum membrane]
(R-HSA-8866834)
PolyUb-CFTR [endosome membrane]
(R-HSA-6782976)
CFTR [endosome membrane]
(R-HSA-6782965)
CFTR [Golgi-associated vesicle membrane]
(R-HSA-5627079)
CFTR [lysosomal membrane]
(R-HSA-5627279)
PolyUb-CFTR [plasma membrane]
(R-HSA-8867595)
PolyUb-CFTR [clathrin-coated endocytic vesicle membrane]
(R-HSA-8869104)
0.646
6
UniProt:Q9HD42 CHMP1A
1
CHMP1A [cytosol]
(R-HSA-917721)
0.556
3
UniProt:Q96GX9 APIP
1
APIP [cytosol]
(R-HSA-1237171)
0.556
3
UniProt:P54252 ATXN3
2
ATXN3 [nucleoplasm]
(R-HSA-6783285)
ATXN3 [cytosol]
(R-HSA-5625607)
0.556
3
UniProt:Q9Y3M2 CBY1
3
CBY1 [nucleoplasm]
(R-HSA-3769210)
pS20-CBY1 [nucleoplasm]
(R-HSA-3769356)
pS20-CBY1 [cytosol]
(R-HSA-3769354)
0.556
3
UniProt:P25788 PSMA3
2
PSMA3 [cytosol]
(R-HSA-68728)
PSMA3 [nucleoplasm]
(R-HSA-174323)
0.556
3
UniProt:Q13200 PSMD2
5
PSMD2 [cytosol]
(R-HSA-68796)
PSMD2 [nucleoplasm]
(R-HSA-174311)
PSMD2 [secretory granule lumen]
(R-HSA-6800919)
PSMD2 [extracellular region]
(R-HSA-6806479)
PSMD2 [ficolin-1-rich granule lumen]
(R-HSA-6800435)
0.556
3
UniProt:P17752 TPH1
1
TPH1 [cytosol]
(R-HSA-976250)
0.556
5
UniProt:O96006 ZBED1
1
ZBED1 [nucleoplasm]
(R-HSA-8956376)
0.556
3
UniProt:P63211 GNGT1
3
S-farn-GNGT1 [photoreceptor disc membrane]
(R-HSA-2530520)
GNGT1 [photoreceptor disc membrane]
(R-HSA-55393)
GNGT1 [plasma membrane]
(R-HSA-167428)
0.556
5
UniProt:O75348 ATP6V1G1
1
ATP6V1G1 [cytosol]
(R-HSA-912578)
0.556
5
UniProt:Q15008 PSMD6
5
PSMD6 [cytosol]
(R-HSA-68804)
PSMD6 [nucleoplasm]
(R-HSA-174316)
PSMD6 [secretory granule lumen]
(R-HSA-6801036)
PSMD6 [extracellular region]
(R-HSA-6806486)
PSMD6 [ficolin-1-rich granule lumen]
(R-HSA-6800440)
0.556
5
UniProt:Q9Y547 HSPB11
2
HSPB11 [ciliary tip]
(R-HSA-5625342)
HSPB11 [cilium]
(R-HSA-5617628)
0.556
3
UniProt:Q6DKK2 TTC19
1
TTC19 [mitochondrial inner membrane]
(R-HSA-9906047)
0.556
5
UniProt:Q96S44 TP53RK
1
TP53RK [nucleoplasm]
(R-HSA-6784489)
0.556
3
UniProt:Q8TAD4 SLC30A5
2
SLC30A5 [secretory granule membrane]
(R-HSA-437105)
SLC30A5 [Golgi membrane]
(R-HSA-9817559)
0.527
2
UniProt:Q15058 KIF14
1
KIF14 [cytosol]
(R-HSA-1629804)
0.527
3
UniProt:Q15363 TMED2
5
TMED2 [endoplasmic reticulum-Golgi intermediate compartment membrane]
(R-HSA-1911531)
TMED2 [endoplasmic reticulum membrane]
(R-HSA-5689480)
TMED2 [ER to Golgi transport vesicle membrane]
(R-HSA-5689847)
TMED2 [transport vesicle]
(R-HSA-6808806)
TMED2 [Golgi membrane]
(R-HSA-6808804)
0.527
2
UniProt:O15155 BET1
3
BET1 [endoplasmic reticulum-Golgi intermediate compartment membrane]
(R-HSA-5688142)
BET1 [transport vesicle]
(R-HSA-6808719)
BET1 [Golgi membrane]
(R-HSA-6807743)
0.483
2
UniProt:P27824 CANX
2
CANX [endoplasmic reticulum lumen]
(R-HSA-195906)
CANX [lumenal side of endoplasmic reticulum membrane]
(R-HSA-983091)
0.483
2
UniProt:P50281 MMP14
4
MMP14 [plasma membrane]
(R-HSA-1442472)
MMP14(21-582) [Golgi lumen]
(R-HSA-1604689)
MMP14 [Golgi lumen]
(R-HSA-1604724)
MMP14 [Golgi membrane]
(R-HSA-9858808)
0.463
2
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