LRP1 [plasma membrane]

Stable Identifier
R-HSA-2424272
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
Prolow-density lipoprotein receptor-related protein 1, LRP1_HUMAN
Icon
LRP1 [plasma membrane] icon
LRP1 [plasma membrane] icon
Locations in the PathwayBrowser
Expand all
External Reference Information
External Reference
UniProt:Q07954 LRP1
Gene Names
LRP1, A2MR, APR
Chain
signal peptide:1-19, chain:20-4544, chain:20-3943, chain:3944-4544, chain:4441-4544
Reference Genes
BioGPS Gene:4035 LRP1
COSMIC (genes):LRP1 LRP1
CTD Gene:4035 LRP1
dbSNP Gene:4035 LRP1
ENSEMBL:ENSG00000123384 LRP1
HGNC:6692 LRP1
KEGG Gene (Homo sapiens):4035 LRP1
Monarch:4035 LRP1
NCBI Gene:4035 LRP1
OMIM:107770 LRP1
UCSC:Q07954 LRP1
Reference Transcript
Other Identifiers
0001050494
11715533_a_at
11715534_a_at
11760039_a_at
1555353_at
16752715
18621
1CR8
1D2L
1J8E
200784_s_at
200785_s_at
22903
2FYJ
2FYL
2KNX
2KNY
3417843
3417844
3417849
3417850
3417852
3417853
3417854
3417855
3417857
3417858
3417859
3417860
3417862
3417863
3417866
3417867
3417868
3417869
3417870
3417871
3417872
3417877
3417878
3417881
3417882
3417884
3417886
3417887
3417888
3417889
3417891
3417892
3417894
3417896
3417897
3417898
3417900
3417901
3417902
3417903
3417905
3417909
3417910
3417911
3417912
3417915
3417916
3417917
3417918
3417920
3417921
3417922
3417923
3417924
3417925
3417927
3417928
3417929
3417931
3417932
3417933
3417935
3417936
3417937
3417938
3417939
3417940
3417941
3417942
3417943
3417944
3417945
3417946
3417947
3417948
3417949
3417950
3417951
3417952
3417955
3417956
3417959
3417960
3417962
3417963
3417964
3417965
3417967
3417968
3417970
3417972
3417973
3417974
3417975
3417977
3417978
3417979
3417981
3417982
3417983
3417984
3417985
3417986
3417987
38775_at
4035
4182
7956301
A_14_P111898
A_23_P124837
A_33_P3391105
AAC64265
AAH45107
ABC40732
AC023237
AC137628
AC137834
AF058427
BC045107
CAA32112
CAA33464
CAB018621
CAD57169
CCDS8932
DQ314873
ENSG00000123384
ENSP00000243077
ENSP00000341264
ENST00000243077
ENST00000243077.7
ENST00000338962
ENST00000338962.8
EntrezGene:4035
EntrezGene:LRP1
g4758685_3p_s_at
GO:0000902
GO:0001523
GO:0001540
GO:0002020
GO:0002265
GO:0002376
GO:0003674
GO:0003723
GO:0005041
GO:0005044
GO:0005509
GO:0005515
GO:0005575
GO:0005622
GO:0005623
GO:0005634
GO:0005737
GO:0005764
GO:0005765
GO:0005768
GO:0005769
GO:0005773
GO:0005886
GO:0005887
GO:0005905
GO:0005925
GO:0006464
GO:0006629
GO:0006810
GO:0006897
GO:0006898
GO:0006909
GO:0006950
GO:0007010
GO:0007034
GO:0007041
GO:0007155
GO:0007165
GO:0007204
GO:0007205
GO:0007267
GO:0007275
GO:0007568
GO:0008150
GO:0008219
GO:0008283
GO:0009056
GO:0010715
GO:0010812
GO:0010875
GO:0010942
GO:0010976
GO:0010977
GO:0014912
GO:0015026
GO:0015031
GO:0016020
GO:0016021
GO:0016192
GO:0016323
GO:0016964
GO:0019899
GO:0021987
GO:0022607
GO:0030136
GO:0030154
GO:0030178
GO:0030198
GO:0030226
GO:0030425
GO:0030666
GO:0031410
GO:0031623
GO:0032050
GO:0032092
GO:0032370
GO:0032374
GO:0032429
GO:0032593
GO:0032956
GO:0032991
GO:0034185
GO:0034330
GO:0035774
GO:0035909
GO:0038023
GO:0038024
GO:0040007
GO:0040011
GO:0042157
GO:0042592
GO:0042953
GO:0043025
GO:0043066
GO:0043167
GO:0043226
GO:0043235
GO:0043277
GO:0043395
GO:0043524
GO:0044242
GO:0044295
GO:0044877
GO:0045056
GO:0045177
GO:0045773
GO:0045807
GO:0046872
GO:0048691
GO:0048694
GO:0048856
GO:0048870
GO:0050766
GO:0051222
GO:0051481
GO:0051895
GO:0060548
GO:0061642
GO:0070325
GO:0070374
GO:0097242
GO:0098797
GO:0150093
GO:0150094
GO:1900149
GO:1900223
GO:1903078
GO:1904109
GO:1904209
GO:1904646
GO:1904754
GO:1905049
GO:1905167
GO:2000587
H0YJ88
HGNC:6692
HPA004182
HPA022903
Hs.89137.0.A1_3p_a_at
Hs2Affx.1.232.S1_3p_s_at
ILMN_1669772
IPR000033
IPR000152
IPR000742
IPR001881
IPR002172
IPR009030
IPR011042
IPR013032
IPR018097
IPR023415
IPR026823
IPR032485
IPR036055
LRP1
LRP1-201
LRP1-202
MIM:107770
MIM:604093
NM_002332
NP_002323
PF00057
PF00058
PF07645
PF12662
PF14670
PF16472
PH_hs_0022761
PR00261
Q6PJ72
Q7Z7K9
SM00135
SM00179
SM00181
SM00192
TC12000521.hg
TC12002395.hg
TC12002396.hg
UPI000000DACF
UPI00001B044F
X13916
X13916_at
X15424
XM_017019303
XP_016874792
Y18524
Participant Of
hasMember
Other forms of this molecule
LRP1 [endocytic vesicle membrane]
LRP1 [plasma membrane]
Inferred To
LRP1 [plasma membrane] (Bos taurus)
LRP1 [plasma membrane] (Danio rerio)
LRP1 [plasma membrane] (Mus musculus)
LRP1 [plasma membrane] (Rattus norvegicus)
Cross References
RefSeq
OpenTargets
GeneCards
PRO
Orphanet
HMDB Protein
PDB
Interactors (8)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:P02649 APOE  9 0.784 23
 UniProt:P30533 AMRP      0.75 4
 UniProt:O00213 APBB1  1 0.704 4
 calcium(2+) [ChEBI:29108]  19 0.609 4
 UniProt:Q15485 FCN2  1 0.558 2
 UniProt:P11226 MBL2  1 0.558 5
 UniProt:Q03350  4 0.499 2
 UniProt:Q63722  1 0.499 4