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Go!
COMP [extracellular region]
Stable Identifier
R-HSA-2426331
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
extracellular region
Synonyms
Cartilage oligomeric matrix protein, COMP_HUMAN
Locations in the PathwayBrowser
Expand all
Extracellular matrix organization (Homo sapiens)
ECM proteoglycans (Homo sapiens)
COMP binds collagen, fibronectin, aggrecan and matrilins (Homo sapiens)
COMP pentamer [extracellular region] (Homo sapiens)
COMP [extracellular region] (Homo sapiens)
COMP pentamer:COMP interactors [extracellular region] (Homo sapiens)
COMP pentamer [extracellular region] (Homo sapiens)
COMP [extracellular region] (Homo sapiens)
Integrin cell surface interactions (Homo sapiens)
COMP binds Integrin alpha5beta1, Integrin alphaVbeta3, CD47 (Homo sapiens)
COMP pentamer [extracellular region] (Homo sapiens)
COMP [extracellular region] (Homo sapiens)
COMP pentamer:Integrin alpha5beta1, Integrin alphaVbeta3, CD47 [plasma membrane] (Homo sapiens)
COMP pentamer [extracellular region] (Homo sapiens)
COMP [extracellular region] (Homo sapiens)
External Reference Information
External Reference
UniProt:P49747 COMP
Gene Names
COMP
Chain
signal peptide:1-20, chain:21-757
Reference Genes
BioGPS Gene:1311 COMP
COSMIC (genes):COMP COMP
CTD Gene:1311 COMP
dbSNP Gene:1311 COMP
ENSEMBL:ENSG00000105664 COMP
ENSEMBL_homo_sapiens_GENE:ENSG00000105664.11 COMP
HGNC:2227 COMP
KEGG Gene (Homo sapiens):1311 COMP
Monarch:1311 COMP
NCBI Gene:1311 COMP
OMIM:600310 COMP
UCSC:P49747 COMP
Reference Transcript
RefSeq:NM_000095.2 COMP
Other Identifiers
11750735_a_at
1311
16870453
205713_PM_s_at
205713_s_at
3855219
3855220
3855221
3855222
3855223
3855225
3855226
3855227
3855229
3855230
3855231
3855232
3855233
3855234
3855235
3855236
3855237
3855238
3855239
3855240
3855241
3855242
3855244
3855245
40161_at
40162_s_at
8035517
A_23_P90436
A_24_P264943
GE53986
GO:0001501
GO:0001503
GO:0002020
GO:0002063
GO:0003012
GO:0003013
GO:0003416
GO:0003417
GO:0005178
GO:0005198
GO:0005201
GO:0005509
GO:0005515
GO:0005518
GO:0005576
GO:0005615
GO:0006915
GO:0006986
GO:0007155
GO:0007596
GO:0008201
GO:0009306
GO:0009887
GO:0010468
GO:0012501
GO:0014829
GO:0016485
GO:0023052
GO:0030154
GO:0030198
GO:0030199
GO:0030282
GO:0030312
GO:0030500
GO:0030509
GO:0031012
GO:0032991
GO:0035264
GO:0035988
GO:0035989
GO:0036122
GO:0042060
GO:0043066
GO:0043226
GO:0043394
GO:0043395
GO:0043588
GO:0048844
GO:0048856
GO:0050877
GO:0050881
GO:0050905
GO:0051216
GO:0051260
GO:0051604
GO:0055001
GO:0060173
GO:0060349
GO:0062023
GO:0065003
GO:0070062
GO:0070527
GO:0090398
GO:0097084
GO:0098868
GO:1900047
GO:1902732
GO:1990079
HMNXSV003054320
ILMN_1677636
L32137_at
PH_hs_0027533
TC19001293.hg
g4557482_3p_s_at
Participates
as a component of
COMP pentamer [extracellular region] (Homo sapiens)
Inferred To
Tsp [extracellular region]
(Drosophila melanogaster)
Comp [extracellular region]
(Mus musculus)
Comp [extracellular region]
(Rattus norvegicus)
comp [extracellular region]
(Danio rerio)
comp [extracellular region]
(Xenopus tropicalis)
Dmel\CG9297 [extracellular region]
(Drosophila melanogaster)
Homologues of COMP [extracellular region]
(Drosophila melanogaster)
COMP [extracellular region]
(Bos taurus)
COMP [extracellular region]
(Canis familiaris)
COMP [extracellular region]
(Gallus gallus)
COMP [extracellular region]
(Sus scrofa)
Cross References
RefSeq
NP_000086.2
OpenTargets
ENSG00000105664
HPA
ENSG00000105664-COMP
GeneCards
P49747
Ensembl
ENSP00000222271
,
ENST00000222271
,
ENST00000425807
,
ENSP00000403792
,
ENSG00000105664
PRO
P49747
Pharos - Targets
P49747
Orphanet
15787
PDB
3FBY
HMDB Protein
HMDBP02410
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:O00244 ATOX1
1
ATOX1 [cytosol]
(R-HSA-3697884)
0.556
3
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