Interaction of DAP12 and CLM7

Stable Identifier
R-HSA-2426566
Type
Reaction [binding]
Species
Homo sapiens
Compartment
plasma membrane
ReviewStatus
5/5
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Interaction of DAP12 and CLM7
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CLM7/TREM5 is a member of the CMRF-35/immune receptor expressed by myeloid cell (IREM) multigene family of immune receptors expressed on myeloid cells. It has a basic residue in its transmembrane domain and a functional tyrosine-based motif in its short cytoplasmic tail. This structural arrangement confers CLM7 the ability to signal through two independent pathways: one through associating with activating adaptor protein DAP12 and the other through the tyrosine motif in its cytoplasmic tail (Martinez-Barriocanal & Sayos 2006).
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as an event of
Orthologous Events
Interaction of DAP12 and CLM7 (Canis familiaris)
Interaction of DAP12 and CLM7 (Mus musculus)
Interaction of DAP12 and CLM7 (Rattus norvegicus)
Interaction of DAP12 and CLM7 (Sus scrofa)
Authored
Garapati, P V  (2012-05-25)
Reviewed
Lanier, LL  (2012-08-09)
Created
Garapati, P V  (2012-08-06)
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