11cROL binds to RLBP1 to form RLBP1:11cROL

Stable Identifier
R-HSA-2454264
Type
Reaction
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

Cellular retinaldehyde-binding protein (RLBP1, CRALBP) (Intres et al. 1994) is abundant in retinal pigment epithelium (RPE) and Muller cells of the retina where it plays a role in sequestering 11-cis retinoids produced during the retinoid cycle. The natural ligands are 11-cis-retinol (11cROL) and 11-cis-retinal (11cRAL) (Crabb et al. 1998).

Literature References
PubMed ID Title Journal Year
9541407 Structural and functional characterization of recombinant human cellular retinaldehyde-binding protein

Crabb, JW, Carlson, A, Chen, Y, Goldflam, S, Intres, R, West, KA, Hulmes, JD, Kapron, JT, Luck, LA, Horwitz, J, Bok, D

Protein Sci. 1998
7929238 Molecular cloning and structural analysis of the human gene encoding cellular retinaldehyde-binding protein

Intres, R, Goldflam, S, Cook, JR, Crabb, JW

J. Biol. Chem. 1994
Participants
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