Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
RDH12 [photoreceptor inner segment membrane]
Stable Identifier
R-HSA-2464787
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
photoreceptor inner segment membrane
Synonyms
Retinol dehydrogenase 12 ecNumber1.1.1.-/ecNumber, RDH12_HUMAN
Icon
Locations in the PathwayBrowser for interactor UniProt:O95630 STAMBP
Expand all
Sensory Perception (Homo sapiens)
Visual phototransduction (Homo sapiens)
The canonical retinoid cycle in rods (twilight vision) (Homo sapiens)
RDH12 reduces atRAL to atROL (Homo sapiens)
RDH12 [photoreceptor inner segment membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q96NR8 RDH12
Gene Names
RDH12, SDR7C2
Chain
chain:1-316
Reference Genes
BioGPS Gene:145226 RDH12
COSMIC (genes):RDH12 RDH12
CTD Gene:145226 RDH12
dbSNP Gene:145226 RDH12
ENSEMBL:ENSG00000139988 RDH12
ENSEMBL_homo_sapiens_GENE:ENSG00000139988.10 RDH12
HGNC:19977 RDH12
KEGG Gene (Homo sapiens):145226 RDH12
Monarch:145226 RDH12
NCBI Gene:145226 RDH12
OMIM:608830 RDH12
UCSC:Q96NR8 RDH12
Reference Transcript
RefSeq:NM_152443.2 RDH12
Other Identifiers
11727251_at
145226
16785709
242998_PM_at
242998_at
3541453
3541461
3541462
3541463
3541464
3541465
3541468
3541469
3541470
3541472
3541474
3541477
3541478
63476_at
7975284
A_23_P37088
GE80080
GO:0001523
GO:0001917
GO:0003824
GO:0004745
GO:0005515
GO:0005783
GO:0005789
GO:0005886
GO:0006629
GO:0007601
GO:0016020
GO:0016491
GO:0042572
GO:0043226
GO:0045494
GO:0050877
GO:0050896
GO:0052650
GO:0060342
GO:0098754
GO:0102354
GO:0110095
HMNXSV003002431
Hs.21299.0.A1_3p_at
ILMN_1792182
PH_hs_0025012
TC14000410.hg
Other forms of this molecule
RDH12 Ala269Glyfs*2 [photoreceptor inner segment membrane]
RDH12 H151N [photoreceptor inner segment membrane]
RDH12 Y226C [photoreceptor inner segment membrane]
RDH12 Q189* [photoreceptor inner segment membrane]
RDH12 A126V [photoreceptor inner segment membrane]
Inferred To
Homologues of RDH12 [photoreceptor inner segment membrane]
(Drosophila melanogaster)
Rdh12 [photoreceptor inner segment membrane]
(Rattus norvegicus)
Dmel\CG2065 [photoreceptor inner segment membrane]
(Drosophila melanogaster)
Rdh1 [photoreceptor inner segment membrane]
(Drosophila melanogaster)
rdh12 [photoreceptor inner segment membrane]
(Danio rerio)
Dmel\CG2070 [photoreceptor inner segment membrane]
(Drosophila melanogaster)
RDH12 [photoreceptor inner segment membrane]
(Bos taurus)
RDH12 [photoreceptor inner segment membrane]
(Canis familiaris)
RDH12 [photoreceptor inner segment membrane]
(Mus musculus)
RDH12 [photoreceptor inner segment membrane]
(Sus scrofa)
RDH11 [photoreceptor inner segment membrane]
(Gallus gallus)
Dmel\CG30495 [photoreceptor inner segment membrane]
(Drosophila melanogaster)
CG30491;CG30495 [photoreceptor inner segment membrane]
(Drosophila melanogaster)
Dmel\CG3842 [photoreceptor inner segment membrane]
(Drosophila melanogaster)
Cross References
RefSeq
NP_689656.2
OpenTargets
ENSG00000139988
HPA
ENSG00000139988-RDH12
GeneCards
Q96NR8
Ensembl
ENSP00000267502
,
ENST00000267502
,
ENSP00000449079
,
ENSG00000139988
,
ENST00000551171
PRO
Q96NR8
Pharos - Targets
Q96NR8
Orphanet
15194
HMDB Protein
HMDBP03034
Interactors (13)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q93062-3 RBPMS
0.556
3
UniProt:Q93062 RBPMS
0.556
3
UniProt:Q6IQ23-2 PLEKHA7
0.556
3
UniProt:Q969T4 UBE2E3
4
UBE2E3 [cytosol]
(R-HSA-947633)
UBE2E3 [nucleoplasm]
(R-HSA-8852108)
Ub-C145-UBE2E3 [nucleoplasm]
(R-HSA-8864208)
Ub-C145-UBE2E3 [cytosol]
(R-HSA-8864162)
0.527
2
UniProt:P62079 TSPAN5
2
TSPAN5 [plasma membrane]
(R-HSA-9010031)
TSPAN5 [endoplasmic reticulum lumen]
(R-HSA-9010081)
0.527
2
UniProt:Q5XPI4 RNF123
2
K63polyUb-RNF123 [cytosol]
(R-HSA-6783055)
RNF123 [cytosol]
(R-HSA-975996)
0.527
2
UniProt:Q3LXA3 TKFC
1
TKFC [cytosol]
(R-HSA-918185)
0.527
2
UniProt:P40855 PEX19
1
PEX19 [cytosol]
(R-HSA-3009036)
0.527
2
UniProt:O95630 STAMBP
1
STAMBP [cytosol]
(R-HSA-5693063)
0.527
2
UniProt:O60361 NME2P1
1
NME2P1 [cytosol]
(R-HSA-6806876)
0.527
2
UniProt:Q13542 4EBP2
0.527
2
UniProt:Q14847 LASP1
0.527
2
UniProt:Q7Z6K5 ARPIN
0.527
2
© 2024
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text