Collagen type XIII binds Integrin alpha1beta1

Stable Identifier
R-HSA-2484965
Type
Reaction
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

Integrin alpha1beta1 is a negative feedback regulator of collagen synthesis (Gardner et al. 1999). CHO cells expressing human integrin alpha1beta1, but not cells expressing integrin alpha2beta1, were able to bind recombinant human collagen type XIII, promoting cell spreading (Nykvist et al. 2000).

Literature References
PubMed ID Title Journal Year
10713152 Distinct recognition of collagen subtypes by alpha(1)beta(1) and alpha(2)beta(1) integrins. Alpha(1)beta(1) mediates cell adhesion to type XIII collagen

Nykvist, P, Tu, H, Ivaska, J, Käpylä, J, Pihlajaniemi, T, Heino, J

J Biol Chem 2000
Participants
Participant Of
Orthologous Events
Authored
Reviewed