Elastin degradation by MMP14

Stable Identifier
R-HSA-2514790
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
General
SVG |   | PPTX  | SBGN
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout

Elastin degradation is regulated by the membrane-associated matrix metalloproteinase MMP14 (Xiong et al. 2009) and associated with aneurisms.

Literature References
PubMed ID Title Journal Year
19010778 Membrane-type 1 matrix metalloproteinase regulates macrophage-dependent elastolytic activity and aneurysm formation in vivo

Xiong, W, Knispel, R, MacTaggart, J, Greiner, TC, Weiss, SJ, Baxter, BT

J. Biol. Chem. 2009
Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
metalloendopeptidase activity of MMP14,TMPRSS6 [plasma membrane]
Physical Entity
Activity
Orthologous Events
Authored
Reviewed
Created
Cite Us!