Reactome | Vitronectin (VTN) binds to C5b:C6:C7

Vitronectin (VTN) binds to C5b:C6:C7

Stable Identifier

R-HSA-2530453

Type

Reaction [binding]

Species

Homo sapiens

Compartment

extracellular region

ReviewStatus

5/5

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Vitronectin interacts with C5b:C6:C7 complex preventing it from the binding with the cell membrane

Literature References

PubMed ID	Title	Journal	Year
7542572	Complement inhibition by human vitronectin involves non-heparin binding domains Charlesworth, JA, Morris, CA, Sheehan, M, Pussell, BA	Clin. Exp. Immunol.	1995
2466593	Complement S-protein (vitronectin) is associated with cytolytic membrane-bound C5b-9 complexes Halstensen, TS, Hugo, F, Preissner, KT, Käflein, R, Mollnes, TE, Bhakdi, S	Clin. Exp. Immunol.	1988
2465906	SC5b-7, SC5b-8 and SC5b-9 complexes of complement: ultrastructure and localization of the S-protein (vitronectin) within the macromolecules Podack, ER, Müller-Eberhard, HJ, Preissner, KP	Eur. J. Immunol.	1989