Reactome | ID1 [nucleoplasm]

ID1 [nucleoplasm]

Stable Identifier

R-HSA-2534101

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

DNA-binding protein inhibitor ID-1, Class B basic helix-loop-helix protein 24, BHLHB24, Inhibitor of DNA binding 1

Locations in the PathwayBrowser for interactor UniProt:P55036

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External Reference Information

External Reference

UniProt:P41134 ID1

Gene Names

ID1, BHLHB24, ID

Chain

chain:1-155

Reference Genes

BioGPS Gene:3397 ID1

COSMIC (genes):ID1 ID1

CTD Gene:3397 ID1

dbSNP Gene:3397 ID1

ENSEMBL:ENSG00000125968 ID1

HGNC:5360 ID1

KEGG Gene (Homo sapiens):3397 ID1

Monarch:3397 ID1

NCBI Gene:3397 ID1

OMIM:600349 ID1

UCSC:P41134 ID1

Reference Transcript

Other Identifiers

0000730048

0000780114

11716195_a_at

11716196_x_at

11753661_a_at

16912362

208937_s_at

3397

36617_at

36618_g_at

36619_r_at

3881392

3881393

3881394

3881395

3881396

3881397

3881398

3881399

3881400

3881401

8061564

ADDON002895.hg

A_14_P121564

A_23_P252306

GE58816

GE81126

GE86461

GO:0000122

GO:0000902

GO:0001525

GO:0001886

GO:0003674

GO:0005515

GO:0005575

GO:0005622

GO:0005634

GO:0005654

GO:0005737

GO:0005794

GO:0005813

GO:0005815

GO:0005856

GO:0006464

GO:0007010

GO:0007155

GO:0007165

GO:0007179

GO:0007275

GO:0007420

GO:0007507

GO:0007623

GO:0008022

GO:0008134

GO:0008150

GO:0008219

GO:0008283

GO:0009058

GO:0010621

GO:0010628

GO:0010629

GO:0014070

GO:0022607

GO:0030154

GO:0030182

GO:0030509

GO:0031648

GO:0032091

GO:0032233

GO:0032922

GO:0032963

GO:0034641

GO:0036164

GO:0040011

GO:0042592

GO:0042802

GO:0043066

GO:0043226

GO:0043392

GO:0043408

GO:0043433

GO:0043534

GO:0043621

GO:0045602

GO:0045668

GO:0045765

GO:0045892

GO:0046677

GO:0046983

GO:0047485

GO:0048511

GO:0048514

GO:0048646

GO:0048856

GO:0048870

GO:0050679

GO:0050774

GO:0060425

GO:0060426

GO:0070628

GO:0071364

GO:0071560

GO:0120163

GO:0140416

GO:1901342

GO:1901653

GO:1903351

GO:1903508

GO:1990090

ILMN_1664861

ILMN_1665832

PH_hs_0024850

S78825_at

TC20000194.hg

g464181_3p_a_at

Participant Of

hasMember

ID1, ID3 [nucleoplasm]

input

ID1 sequesters ETS2

hasComponent

p-T72-ETS2:ID1 [nucleoplasm]

Inferred To

emc [nucleoplasm] (Drosophila melanogaster)

id1 [nucleoplasm] (Danio rerio)

Id1 [nucleoplasm] (Gallus gallus)

Id1 [nucleoplasm] (Mus musculus)

Id1 [nucleoplasm] (Rattus norvegicus)

ID1 [nucleoplasm] (Bos taurus)

ID1 [nucleoplasm] (Sus scrofa)

Cross References

RefSeq

NP_851998.1, NP_002156.2

Target Pathogen

5b354852be737e166372ea9a

OpenTargets

ENSG00000125968

GeneCards

P41134

HPA

ENSG00000125968-ID1

Ensembl

ENSG00000125968, ENST00000376105, ENST00000376112, ENSP00000365280, ENSP00000365273

ZINC target

P41134

PRO

P41134

Interactors (17)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q03135 CAV1	5	CAV1 [early endosome membrane] (R-HSA-5368451) CAV1 [plasma membrane] (R-HSA-534994) CAV1 [Golgi membrane] (R-HSA-204504) CAV1 [lipid droplet] (R-HSA-163510) CAV1 [endocytic vesicle membrane] (R-HSA-535009)	0.602	6
UniProt:P15173 MYOG	1	MYOG [nucleoplasm] (R-HSA-445160)	0.601	4
UniProt:P22607 FGFR3	40	FGFR3 K650N [plasma membrane] (R-HSA-1614406) FGFR3 K650T [plasma membrane] (R-HSA-1614411) FGFR3 K650M [plasma membrane] (R-HSA-1614402) FGFR3 K650Q [plasma membrane] (R-HSA-1614410) FGFR3 A391E [plasma membrane] (R-HSA-1614390) FGFR3 K650E [plasma membrane] (R-HSA-1614400) FGFR3 G380R [plasma membrane] (R-HSA-1614398) FGFR3 G382D [plasma membrane] (R-HSA-2018740) FGFR3 795fs139 [plasma membrane] (R-HSA-1614387) FGFR3 [plasma membrane] (R-HSA-2038357) FGFR3 S371C [plasma membrane] (R-HSA-1614421) FGFR3 Y373C [plasma membrane] (R-HSA-1614424) FGFR3 G370C [plasma membrane] (R-HSA-1614394) FGFR3 R248C [plasma membrane] (R-HSA-1614419) p-6Y-FGFR3 S371C [plasma membrane] (R-HSA-2011886) p-6Y-FGFR3 G370C [plasma membrane] (R-HSA-2011883) p-6Y-FGFR3 Y373C [plasma membrane] (R-HSA-2011889) p-6Y-FGFR3 795fs139 [plasma membrane] (R-HSA-2038360) p-6Y-FGFR3 R248C [plasma membrane] (R-HSA-2011884) pY-FGFR3 [plasma membrane] (R-HSA-2038368) p-6Y-FGFR3 K650Q [plasma membrane] (R-HSA-2032962) p-6Y-FGFR3 K650N [plasma membrane] (R-HSA-2032961) p-6Y-FGFR3 K650E [plasma membrane] (R-HSA-2032952) p-6Y-FGFR3 K650M [plasma membrane] (R-HSA-2032959) p-6Y-FGFR3 G380R [plasma membrane] (R-HSA-2032946) p-6Y-FGFR3 G382D [plasma membrane] (R-HSA-2032950) p-6Y-FGFR3 K650T [plasma membrane] (R-HSA-2032966) p-6Y-FGFR3 A391E [plasma membrane] (R-HSA-2065835) p-4Y FGFR3(23-760)-TACC3(612-838) fusion [plasma membrane] (R-HSA-8853147) p-4Y FGFR3(23-760)-TACC3(647-838) fusion [plasma membrane] (R-HSA-8853155) p-4Y FGFR3(23-793)-TACC3(143-838) fusion [plasma membrane] (R-HSA-8853145) p-4Y FGFR3(23-758)-TACC3(549-838) fusion [plasma membrane] (R-HSA-8853129) p-4Y FGFR3(23-758)-TACC3(649-838) fusion [plasma membrane] (R-HSA-8853151) p-4Y FGFR3(23-760)-BAIAP2L1(18-522) fusion [plasma membrane] (R-HSA-8853128) FGFR3(23-760)-TACC3(612-838) fusion [plasma membrane] (R-HSA-8853144) FGFR3(23-760)-BAIAP2L1(18-522) fusion [plasma membrane] (R-HSA-8853131) FGFR3(23-793)-TACC3(143-838) fusion [plasma membrane] (R-HSA-8853152) FGFR3(23-758)-TACC3(549-838) fusion [plasma membrane] (R-HSA-8853124) FGFR3(23-758)-TACC3(649-838) fusion [plasma membrane] (R-HSA-8853125) FGFR3(23-760)-TACC3(647-838) fusion [plasma membrane] (R-HSA-8853127)	0.556	3
UniProt:P06396 GSN	7	GSN [ficolin-1-rich granule lumen] (R-HSA-6801465) GSN(200-270) [extracellular region] (R-HSA-976940) GSN [extracellular region] (R-HSA-6806510) GSN [secretory granule lumen] (R-HSA-6801486) GSN(404-782) [cytosol] (R-HSA-350272) GSN(28-403) [cytosol] (R-HSA-201618) GSN [cytosol] (R-HSA-350275)	0.556	3
UniProt:Q7Z699 SPRED1	2	SPRED1 [cytosol] (R-HSA-5654207) SPRED1 [plasma membrane] (R-HSA-5658225)	0.556	3
UniProt:P15923-3 TCF3			0.556	3
UniProt:P13349 MYF5	1	MYF5 [nucleoplasm] (R-HSA-445158)	0.556	5
UniProt:Q9Y649 Q9Y649			0.556	3
UniProt:Q99081-3 TCF12			0.556	3
UniProt:P15884-3 TCF4			0.556	3
UniProt:P28329-3 P283293			0.556	3
UniProt:Q9NQ33 ASCL3			0.556	3
UniProt:A6NI15 MSGN1			0.556	5
UniProt:P15884 TCF4	1	TCF4 [nucleoplasm] (R-HSA-445672)	0.547	3
UniProt:O14936 CASK	1	CASK [cytosol] (R-HSA-373631)	0.508	3
UniProt:Q9UKG1 APPL1	1	APPL1 [endosome membrane] (R-HSA-373630)	0.488	2
UniProt:P55036 PSMD4	2	PSMD4 [cytosol] (R-HSA-68800) PSMD4 [nucleoplasm] (R-HSA-174330)	0.463	2

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