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HSPG2(22-?) [extracellular region]
Stable Identifier
R-HSA-2534251
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
extracellular region
Synonyms
HSPG2 N-term fragment, Perlecan N-term fragment
Locations in the PathwayBrowser
Expand all
Extracellular matrix organization (Homo sapiens)
Degradation of the extracellular matrix (Homo sapiens)
HSPG2 (perlecan) degradation by MMP13, CTSS (Homo sapiens)
HSPG2(22-?) [extracellular region] (Homo sapiens)
HSPG2 (perlecan) degradation by MMP14, MMP15 (Homo sapiens)
HSPG2(22-?) [extracellular region] (Homo sapiens)
HSPG2 (perlecan) degradation by MMP3, plasmin, (MMP12) (Homo sapiens)
HSPG2(22-?) [extracellular region] (Homo sapiens)
External Reference Information
External Reference
UniProt:P98160 HSPG2
Gene Names
HSPG2
Chain
signal peptide:1-21, chain:22-4391, chain:3687-4391, chain:4197-4391
Reference Genes
COSMIC (genes):HSPG2 HSPG2
dbSNP Gene:3339 HSPG2
ENSEMBL:ENSG00000142798 HSPG2
Participates
as an output of
Degradation of HSPG2 by Mmp13 and Ctss (Homo sapiens)
HSPG2 (perlecan) degradation by MMP13, CTSS (Homo sapiens)
HSPG2 (perlecan) degradation by MMP3, plasmin, (MMP12) (Homo sapiens)
HSPG2 (perlecan) degradation by MMP14, MMP15 (Homo sapiens)
Other forms of this molecule
HSPG2(22-4196) [extracellular region]
HS(4)-HSPG2 [plasma membrane]
HS(6)-HSPG2 [plasma membrane]
HS(2)-HSPG2 [plasma membrane]
HS(1)-HSPG2 [plasma membrane]
HS(3)-HSPG2 [plasma membrane]
HS(5)-HSPG2 [plasma membrane]
HSPG2(3687-4391) [extracellular region]
XylS-HSPG2(22-4391) [Golgi lumen]
Gal-Xyl-HSPG2 [Golgi lumen]
HSPG2(22-4391) [Golgi lumen]
Gal-Gal-Xyl-HSPG2 [Golgi lumen]
GlcA-Gal-Gal-Xyl-HSPG2 [Golgi lumen]
HS(3)-HSPG2 [Golgi lumen]
HS(4)-HSPG2 [Golgi lumen]
HS(2)-HSPG2 [Golgi lumen]
HS(1)-HSPG2 [Golgi lumen]
Heparan(4)-HSPG2 [Golgi lumen]
Heparan(3)-HSPG2 [Golgi lumen]
Heparan(2)-HSPG2 [Golgi lumen]
Heparan(1)-HSPG2 [Golgi lumen]
Heparan-HSPG2 [Golgi lumen]
HS(5)-HSPG2 [Golgi lumen]
HS(6)-HSPG2 [Golgi lumen]
HS(6)-HSPG2 [lysosomal lumen]
HSPG2(22-4391) [lysosomal lumen]
HSPG2(22-4391) [extracellular region]
Heparan sulfate-HSPG2 [extracellular region]
HSPG2(?-4391) [extracellular region]
HSPG2(4197-4391) [extracellular region]
Inferred To
DIP-epsilon [extracellular region]
(Drosophila melanogaster)
DIP-kappa [extracellular region]
(Drosophila melanogaster)
DIP-zeta [extracellular region]
(Drosophila melanogaster)
DIP-alpha [extracellular region]
(Drosophila melanogaster)
HSPG2(22-?) [extracellular region]
(Caenorhabditis elegans)
Lac [extracellular region]
(Drosophila melanogaster)
CT35363 [extracellular region]
(Drosophila melanogaster)
rig-5 [extracellular region]
(Caenorhabditis elegans)
Homologues of HSPG2(22-?) [extracellular region]
(Caenorhabditis elegans)
Homologues of HSPG2(22-?) [extracellular region]
(Drosophila melanogaster)
DIP-eta [extracellular region]
(Drosophila melanogaster)
fipi [extracellular region]
(Drosophila melanogaster)
CT35293 [extracellular region]
(Drosophila melanogaster)
DIP-delta [extracellular region]
(Drosophila melanogaster)
DIP-gamma [extracellular region]
(Drosophila melanogaster)
DIP-beta [extracellular region]
(Drosophila melanogaster)
DIP-theta [extracellular region]
(Drosophila melanogaster)
DIP-lambda [extracellular region]
(Drosophila melanogaster)
Interactors (5)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P35968 KDR
5
p-6Y-VEGFR2 [plasma membrane]
(R-HSA-4420103)
VEGFR2 [plasma membrane]
(R-HSA-195382)
p-Y801,Y1054,Y1175-KDR [plasma membrane]
(R-HSA-9860484)
VEGFR2(20-662)insVAGTWTSGLMSL-PDGFRA(471-1089) fusion [plasma membrane]
(R-HSA-9673613)
p-11Y-VEGFR2(20-662)insVAGTWTSGLMSL-PDGFRA(471-1089) [plasma membrane]
(R-HSA-9673636)
0.719
5
UniProt:P05230 FGF1
1
FGF1 [extracellular region]
(R-HSA-189856)
0.564
3
ChEBI:28304 HEPARIN
0.564
2
UniProt:P28799 GRN
2
GRN [azurophil granule lumen]
(R-HSA-6799168)
GRN [extracellular region]
(R-HSA-6806217)
0.53
3
UniProt:Q9H9D4 ZN408
0.527
2
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