Scavenger receptor CD36 has been reported to function as an essential co-receptor involved in recognition of LTA and certain diacylated lipoproteins and presenting them to the TLR2:TLR6 heterodimer at the cell surface. CD14, a GPI-anchored molecule found on the cell surface of human phagocytes, has been also implicated in TLR2:TLR6 signaling [Stuart L et al 2005; Hoebe KP et al 2005; Triantafilou M et al 2006; Nilsen NJ et al 2008]
Triantafilou, M, Gamper, FG, Haston, RM, Mouratis, MA, Morath, S, Hartung, T, Triantafilou, K
Bas, S, Neff, L, Vuillet, M, Spenato, U, Seya, T, Matsumoto, M, Gabay, C
© 2021 Reactome
