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BRIP1 [cytosol]
Stable Identifier
R-HSA-2564781
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
apo-BRIP1 (apo-FANCJ), apo-FANCJ, apo-BRIP1, Fanconi anemia group J protein, FANCJ_HUMAN
Locations in the PathwayBrowser
Expand all
Metabolism (Homo sapiens)
Cytosolic iron-sulfur cluster assembly (Homo sapiens)
CIA Targeting Complex transfers 4Fe-4S cluster to apoproteins (Homo sapiens)
Apoprotein Lacking 4Fe-4S Cluster [cytosol] (Homo sapiens)
BRIP1 [cytosol] (Homo sapiens)
Holoprotein Containing 4Fe-4S Cluster [cytosol] (Homo sapiens)
holo-BRIP1 (holo-FANCJ) [cytosol] (Homo sapiens)
BRIP1 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9BX63 BRIP1
Gene Names
BRIP1, BACH1, FANCJ
Chain
chain:1-1249
Reference Genes
BioGPS Gene:83990 BRIP1
COSMIC (genes):BRIP1 BRIP1
CTD Gene:83990 BRIP1
dbSNP Gene:83990 BRIP1
ENSEMBL:ENSG00000136492 BRIP1
ENSEMBL_homo_sapiens_GENE:ENSG00000136492.10 BRIP1
HGNC:20473 BRIP1
KEGG Gene (Homo sapiens):83990 BRIP1
Monarch:83990 BRIP1
NCBI Gene:83990 BRIP1
OMIM:605882 BRIP1
UCSC:Q9BX63 BRIP1
Reference Transcript
RefSeq:NM_032043.2 BRIP1
Other Identifiers
11736601_at
11736602_at
16847432
221703_PM_at
221703_at
235609_PM_at
235609_at
3765583
3765584
3765585
3765586
3765587
3765588
3765589
3765590
3765591
3765598
3765599
3765605
3765606
3765608
3765610
3765611
3765612
3765614
3765616
3765617
3765619
3765623
3765625
3765627
3765628
3765629
3765630
3765631
3765632
3765634
3765635
3765636
55362_at
62361_at
74375_at
8017262
83990
A_23_P15844
A_24_P410468
GE83302
GO:0000077
GO:0000166
GO:0003676
GO:0003677
GO:0003678
GO:0003682
GO:0003724
GO:0003824
GO:0004386
GO:0005515
GO:0005524
GO:0005634
GO:0005635
GO:0005654
GO:0005737
GO:0006139
GO:0006281
GO:0006289
GO:0006302
GO:0006310
GO:0006351
GO:0006355
GO:0006357
GO:0006974
GO:0007059
GO:0007129
GO:0007283
GO:0007284
GO:0007286
GO:0008285
GO:0008584
GO:0009636
GO:0010629
GO:0010705
GO:0016787
GO:0016818
GO:0016887
GO:0022414
GO:0023052
GO:0030154
GO:0031965
GO:0032508
GO:0035825
GO:0043139
GO:0043226
GO:0046872
GO:0048856
GO:0051026
GO:0051276
GO:0051536
GO:0051539
GO:0070532
GO:0071295
GO:0071456
GO:0072520
GO:0140013
GO:0140097
GO:0140098
GO:0140657
GO:1904385
GO:1990918
HMNXSV003015180
Hs.87507.0.A1_3p_at
ILMN_1760757
TC17001769.hg
g13661818_3p_at
Participates
as a component of
holo-BRIP1 (holo-FANCJ) [cytosol] (Homo sapiens)
as a member of
Apoprotein Lacking 4Fe-4S Cluster [cytosol] (Homo sapiens)
Other forms of this molecule
p-S990,Ac-K1249-BRIP1 [nucleoplasm]
Cross References
RefSeq
NP_114432.2
OpenTargets
ENSG00000136492
GeneCards
Q9BX63
HPA
ENSG00000136492-BRIP1
Ensembl
ENST00000683039
,
ENST00000682453
,
ENST00000577598
,
ENSP00000259008
,
ENST00000259008
,
ENSP00000464654
,
ENSG00000136492
,
ENSP00000506943
,
ENSP00000508303
PRO
Q9BX63
Pharos - Targets
Q9BX63
Orphanet
15379
PDB
1T29
,
1T15
,
3AL3
HMDB Protein
HMDBP11734
Interactors (6)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P38398 BRCA1
20
polySUMO2,3-BRCA1 [nucleoplasm]
(R-HSA-2997624)
monoSUMO1-K109-BRCA1 [nucleoplasm]
(R-HSA-2997644)
BRCA1 M1411T [nucleoplasm]
(R-HSA-9702140)
BRCA1 M1400V [nucleoplasm]
(R-HSA-9701202)
BRCA1 L1407P [nucleoplasm]
(R-HSA-9702135)
BRCA1 Y777* [nucleoplasm]
(R-HSA-9702765)
BRCA1 S1009* [nucleoplasm]
(R-HSA-9702755)
BRCA1 P724Lfs*12 [nucleoplasm]
(R-HSA-9703778)
BRCA1 S451* [nucleoplasm]
(R-HSA-9702754)
BRCA1 S864* [nucleoplasm]
(R-HSA-9702752)
BRCA1 P897Kfs*5 [nucleoplasm]
(R-HSA-9703782)
BRCA1 N555Kfs*17 [nucleoplasm]
(R-HSA-9703781)
BRCA1 Y1127Sfs*6 [nucleoplasm]
(R-HSA-9703780)
BRCA1 S886Cfs*16 [nucleoplasm]
(R-HSA-9703802)
BRCA1 V83Cfs*2 [nucleoplasm]
(R-HSA-9703800)
BRCA1 T464Pfs*11 [nucleoplasm]
(R-HSA-9703807)
BRCA1 G813Dfs*2 [nucleoplasm]
(R-HSA-9703549)
BRCA1 V340Gfs*6 [nucleoplasm]
(R-HSA-9703804)
BRCA1 Y655* [nucleoplasm]
(R-HSA-9702769)
BRCA1 W372* [nucleoplasm]
(R-HSA-9702768)
0.979
33
UniProt:P40692 MLH1
3
MLH1 S252* [nucleoplasm]
(R-HSA-5444526)
MLH1 H329P [nucleoplasm]
(R-HSA-5444512)
MLH1 [nucleoplasm]
(R-HSA-912495)
0.886
18
UniProt:P54278 PMS2
3
PMS2 R134* [nucleoplasm]
(R-HSA-5632982)
PMS2 R628* [nucleoplasm]
(R-HSA-5632980)
PMS2 [nucleoplasm]
(R-HSA-5357527)
0.69
5
UniProt:P54132 BLM
2
4SUMO2,3-BLM [nucleoplasm]
(R-HSA-4568883)
BLM [nucleoplasm]
(R-HSA-174881)
0.672
16
UniProt:Q96T76 MMS19
1
MMS19 [cytosol]
(R-HSA-2161121)
0.577
4
UniProt:Q9BPX1 HSD17B14
1
HSD17B14 [cytosol]
(R-HSA-6810587)
0.556
3
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