Dissociation of the COP1-p53 complex

Stable Identifier
R-HSA-264435
Type
Reaction [dissociation]
Species
Homo sapiens
Compartment
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ATM-dependent phosphorylation of COP1 on Ser(387) results in disruption of the COP1-p53 complex (Dornan et al., 2006)

Literature References
PubMed ID Title Journal Year
16931761 ATM engages autodegradation of the E3 ubiquitin ligase COP1 after DNA damage

Dornan, D, Shimizu, H, Mah, A, Dudhela, T, Eby, M, O'Rourke, K, Seshagiri, S, Dixit, VM

Science 2006
Participants
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Orthologous Events
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