Autoubiquitination of phospho-COP1(Ser-387 )

Stable Identifier
R-HSA-264444
Type
Reaction [transition]
Species
Homo sapiens
Compartment
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ATM phosphorylation promotes autoubiquitination of COP1 in vitro (Dornan et al., 2006). The number of ubiquitin molecules shown in this reaction is set arbitrarily at 4.

Literature References
PubMed ID Title Journal Year
16931761 ATM engages autodegradation of the E3 ubiquitin ligase COP1 after DNA damage

Dornan, D, Shimizu, H, Mah, A, Dudhela, T, Eby, M, O'Rourke, K, Seshagiri, S, Dixit, VM

Science 2006
Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
ubiquitin-protein transferase activity of p-S387-RFWD2 [cytosol]
Physical Entity
Activity
Orthologous Events
Authored
Reviewed
Created