Loading of acetylcholine in synaptic vesicles

Stable Identifier
R-HSA-264615
Type
Reaction [transition]
Species
Homo sapiens
Compartment
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Acetylcholine is actively transported from the cytosol to the lumen of the synaptic vesicle by vesicular acetylcholine transporter. Two protons are exchanged for 1 molecule of acetylcholine. The vesicular acetylcholine transporter is located in the membrane of the synaptic vesicle.

Literature References
PubMed ID Title Journal Year
8071310 Functional identification of a vesicular acetylcholine transporter and its expression from a "cholinergic" gene locus

Erickson, JD, Varoqui, H, Schäfer, MK, Modi, W, Diebler, MF, Weihe, E, Rand, J, Eiden, LE, Bonner, TI, Usdin, TB

J Biol Chem 1994
Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
acetylcholine transmembrane transporter activity of SLC18A3 [clathrin-sculpted acetylcholine transport vesicle membrane]
Physical Entity
Activity
Orthologous Events
Authored
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